This is an old revision of this page, as edited by Addbot (talk | contribs) at 19:09, 15 March 2013 (Bot: Migrating 1 interwiki links, now provided by Wikidata on d:q2989497). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.
Revision as of 19:09, 15 March 2013 by Addbot (talk | contribs) (Bot: Migrating 1 interwiki links, now provided by Wikidata on d:q2989497)(diff) ← Previous revision | Latest revision (diff) | Newer revision → (diff)| Hydroxymethylglutaryl-CoA reductase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.1.1.88 | ||||||||
| CAS no. | 37250-24-1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Hydroxymethylglutaryl-CoA reductase (EC 1.1.1.88, beta-hydroxy-beta-methylglutaryl coenzyme A reductase, beta-hydroxy-beta-methylglutaryl CoA-reductase, 3-hydroxy-3-methylglutaryl coenzyme A reductase, hydroxymethylglutaryl coenzyme A reductase) is an enzyme with system name (R)-mevalonate:NAD oxidoreductase (CoA-acylating). This enzyme catalise the following chemical reaction
- (R)-mevalonate + CoA + 2 NAD 3-hydroxy-3-methylglutaryl-CoA + 2 NADH + 2 H
3-hydroxy-3-methylglutaryl-CoA + 2 NADH + 2 HReferences
- Fimognari, G.M. and Rodwell, V.W. (1965). "Substrate-competitive inhibition of bacterial mevalonate:nicotinamide-adenine dinucleotide oxidoreductase (acylating CoA)". Biochemistry. 4: 2086–2090.
{{cite journal}}: CS1 maint: multiple names: authors list (link)
External links
- Hydroxymethylglutaryl-CoA+reductase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)