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Alexander Fleming

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Sir Alexander Fleming
FRSE, FRS, FRCS(Eng)
Born(1881-08-06)6 August 1881
Lochfield, Ayrshire, Scotland
Died11 March 1955(1955-03-11) (aged 73)
London, England
NationalityScottish
CitizenshipUnited Kingdom
Alma materRoyal Polytechnic Institution
St Mary's Hospital Medical School
Imperial College London
Known forDiscovery of penicillin
AwardsNobel Prize in Physiology or Medicine (1945)
Scientific career
FieldsBacteriology, immunology
Signature

Sir Alexander Fleming, FRSE, FRS, FRCS(Eng) (6 August 1881 – 11 March 1955) was a Scottish biologist, pharmacologist and botanist. He wrote many articles on bacteriology, immunology, and chemotherapy. His best-known discoveries are the enzyme lysozyme in 1923 and the antibiotic substance penicillin from the mould Penicillium notatum in 1928, for which he shared the Nobel Prize in Physiology or Medicine in 1945 with Howard Florey and Ernst Boris Chain.

In 1999, Time magazine named Fleming one of the 100 Most Important People of the 20th Century, stating:

It was a discovery that would change the course of history. The active ingredient in that mould, which Fleming named penicillin, turned out to be an infection-fighting agent of enormous potency. When it was finally recognized for what it was, the most efficacious life-saving drug in the world, penicillin would alter forever the treatment of bacterial infections. By the middle of the century, Fleming's discovery had spawned a huge pharmaceutical industry, churning out synthetic penicillins that would conquer some of mankind's most ancient scourges, including syphilis, gangrene and tuberculosis.


Fleming's first wife, Sarah, died in 1949. Their only child, Robert Fleming, became a general medical practitioner. After Sarah's death, Fleming married Dr. Amalia Koutsouri-Vourekas, a Greek colleague at St. Mary's, on 9 April 1953; she died in 1986.

Death

In 1955, Fleming died at his home in London of a heart attack. He was buried in St Paul's Cathedral.

Honours, awards and achievements

Display of Fleming's awards, including his Nobel Prize. Also shows a sample of penicillin and an example of an early apparatus for preparing penicillin.
Fleming (centre) receiving the Nobel prize from King Gustaf V of Sweden (right) in 1945
Faroe Islands stamp commemorating Fleming

His discovery of penicillin had changed the world of modern medicine by introducing the age of useful antibiotics; penicillin has saved, and is still saving, millions of people around the world.

The laboratory at St Mary's Hospital where Fleming discovered penicillin is home to the Fleming Museum, a popular London attraction. His alma mater, St Mary's Hospital Medical School, merged with Imperial College London in 1988. The Sir Alexander Fleming Building on the South Kensington campus was opened in 1998 and is now one of the main preclinical teaching sites of the Imperial College School of Medicine.

His other alma mater, the Royal Polytechnic Institution (now the University of Westminster) has named one of its student halls of residence Alexander Fleming House, which is near to Old Street.

See also

Media related to Alexander Fleming at Wikimedia Commons

Bibliography

  • The Life Of Sir Alexander Fleming, Jonathan Cape, 1959. Maurois, André.
  • Nobel Lectures,the Physiology or Medicine 1942–1962, Elsevier Publishing Company, Amsterdam, 1964
  • An Outline History of Medicine. London: Butterworths, 1985. Rhodes, Philip.
  • The Cambridge Illustrated History of Medicine. Cambridge, England: Cambridge University Press, 1996. Porter, Roy, ed.
  • Penicillin Man: Alexander Fleming and the Antibiotic Revolution, Stroud, Sutton, 2004. Brown, Kevin.
  • Alexander Fleming: The Man and the Myth, Oxford University Press, Oxford, 1984. Macfarlane, Gwyn
  • Fleming, Discoverer of Penicillin, Ludovici, Laurence J., 1952

References

  1. ^ "Alexander Fleming Biography". Les Prix Nobel. The Nobel Foundation. 1945. Retrieved 27 March 2011.
  2. ^ "Alexander Fleming – Time 100 People of the Century". Time. 29 March 1999. It was a discovery that would change the course of history. The active ingredient in that mould, which Fleming named penicillin, turned out to be an infection-fighting agent of enormous potency. When it was finally recognized for what it was, the most efficacious life-saving drug in the world, penicillin would alter forever the treatment of bacterial infections. By the middle of the century, Fleming's discovery had spawned a huge pharmaceutical industry, churning out synthetic penicillins that would conquer some of mankind's most ancient scourges, including syphilis, gangrene and tuberculosis.
  3. "Alexander Fleming". FamousScientists.org. Retrieved 15 December 2011.
  4. "Sir Alexander Fleming – Biography". Nobelprize.org. Retrieved 25 October 2011.
  5. Roberts, Michael (2001). Biology (2, illustrated ed.). Nelson Thornes. p. 105. ISBN 0-7487-6238-8. Retrieved 4 March 2012. Penicillin is just one of a very large number of drugs which today are used by doctors to treat people with diseases. {{cite book}}: Unknown parameter |coauthors= ignored (|author= suggested) (help)
  6. "100,000 visitors in 6 days". National Museums Scotland. 3 August 2011. Retrieved 4 March 2012.
  7. "People of the century". P. 78. CBS News. Simon & Schuster, 1999
  8. "100 great Britons - A complete list". Daily Mail. Retrieved 3 August 2012
  9. ^ Edward Lewine (2007). "Death and the Sun: A Matador's Season in the Heart of Spain". p. 123. Houghton Mifflin Harcourt, 2007
  10. "Banknote designs mark Homecoming". BBC News. 14 January 2008. Archived from the original on 25 January 2009. Retrieved 20 January 2009. {{cite news}}: Unknown parameter |deadurl= ignored (|url-status= suggested) (help)

External links

Academic offices
Preceded byAlastair Sim Rector of the University of Edinburgh
1951–1954
Succeeded bySydney Smith
Laureates of the Nobel Prize in Physiology or Medicine
1901–1925
1926–1950
1951–1975
1976–2000
2001–present

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