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Tincture

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Revision as of 13:11, 20 October 2013 by Andy Dingley (talk | contribs) (Reverted 1 edit by 128.103.233.233 (talk): Rv unexplained deletion. (TW))(diff) ← Previous revision | Latest revision (diff) | Newer revision → (diff) This article is about alcoholic liquids. For the colors used in a coat of arms, see tincture (heraldry).
A tincture prepared from white willow bark and ethanol

A tincture is typically an alcoholic extract of plant or animal material or solution of such or of a low volatility substance (such as iodine and mercurochrome). To qualify as an alcoholic tincture, the extract should have an ethanol percentage of at least 40–60% or 80–120 proof. Sometimes even a 90% or 180 proof tincture is achieved. In herbal medicine, alcoholic tinctures are made with various concentrations of ethanol, 25% being the most common. Other concentrations include 45% and 90%.

Herbal tinctures are not always made using ethanol as the solvent, though this is most commonly the case. Other solvents include vinegar, glycerol, ether and propylene glycol, not all of which can be used for internal consumption. Ethanol has the advantage of being an excellent solvent for both acidic and basic (alkaline) constituents.
Glycerine can also be used, but when used in tincturing fashion is generally a poorer solvent. Vinegar, being acidic, is a better solvent for obtaining alkaloids but a poorer solvent for acidic components. For individuals who chose not to imbibe alcohol, non-alcoholic e,g., (glycerite) extracts offer an alternative for preparations meant to be taken internally.

Alcohol cannot be subjected to high temperatures, so its use is considered a self-limiting 'non-critical' passive methodology. Glycerol, utilized in a non-critical fashion as it was in early Eclectic medicine studies, is typically seen as inferior to alcohol, whereas if glycerol is subjected to an innovative synchronous serialized methodology now being acknowledged in the industry, the extractive potential of glycerol use this way is quite astounding and far exceeds the weak extractive potential for a tincturing methodology. Therefore, newer glycerite products are showing great promise and even rivaling alcoholic tinctures in many ways.

Some solutions of volatile or nonvolatile substances are traditionally called spirits, regardless of whether obtained by distillation or not and whether or not they even contain alcohol. In chemistry, a tincture is a solution that has alcohol as its solvent.

General method of preparation

  • Herbs are put in a container and a spirit of 40% or more ethanol is added, 80 proof Vodka or 190 proof Everclear, for example.
  • The jar is left to stand for 2–3 weeks and shaken occasionally in order to maximize extraction.

More accurate measuring can be done by combining 1 part herbs with a water-ethanol mixture of 2–10 parts, depending on the herb itself. For most tinctures, however, 1 part water to 5 parts ethanol is typical.

Examples

Some examples that were formerly common in medicine include:

Examples of spirits include:

Advantages

Ethanol is able to dissolve substances which are less soluble in water, while at the same time the water content can dissolve the substances less soluble in ethanol. One can sometimes vary the proportion of ethanol and water to produce tinctures with different characteristics due to the distinct solvent properties of these two. Tincture of calendula is commonly tinctured at either 25% or 90% ethanol. The alcohol content also acts as a preservative.

Disadvantages

Ethanol has a tendency to denature some organic compounds, rendering them so changed as to be ineffective. This is one reason why ethanol is an antimicrobial. This tendency can also have undesirable effects when extracting botanical constituents, for instance, polysaccharides. Certain other constituents, common among them proteins, can become irreversibly denatured, or "pickled" in a manner of speaking. Also, extracted for highly complex aromatic components are denatured by alcohol's intrinsic cleaving action upon an aromatic's complex structure into simpler inert-rendered compounds. A basic tenet of organic chemistry teaches that anytime a biologically viable component is denatured, it will reduce or negate its prior biological viability. This fact must be considered by the clinician and/or consumer from both the standpoint of efficacy and dosage when choosing ethanol-based botanical tinctures.

Although ether and propylene glycol based tinctures are not suitable for internal consumption, they are used in preparations such as personal care cremes and ointments.

See also

  • Nalewka - a traditional Polish category of alcoholic tincture.
  • Infusion - a water or oil based extract with similar historical uses to a tincture.
  • Elixir - A pharmaceutical preparation containing an active ingredient that is dissolved in a solution containing some percentage of ethyl alcohol.
  • Extract
  • Topical - categorization of topical skin preparation options

References

  1. ^ Groot Handboek Geneeskrachtige Planten by Geert Verhelst
  2. The Pharmacopoeia of the United States, 1850 ed.
Routes of administration
Routes of administration, dosage forms
Oral
Digestive tract (enteral)
Solids
Liquids
Oral mucosa (buccal, sublabial, sublingual)
Solids
Liquids
Respiratory tract (inhalation)
Solids
0
0
Liquids
Gas
Ophthalmic,
otic, nasal
Urogenital
  • Ointment
  • Pessary
  • Vaginal ring
  • Douche
  • Intrauterine device (IUD)
  • Extra-amniotic infusion
  • Intravesical infusion
  • Rectal (enteral)
    Dermal (topical)
  • Ointment
  • Topical cream
  • Topical gel
  • Liniment
  • Paste
  • Film
  • DMSO solution
  • Iontophoresis
  • Hydrogel
  • Liposomes
  • Transfersome vesicles
  • Cream
  • Lotion
  • Lip balm
  • Medicated shampoo
  • Dermal patch
  • Transdermal patch
  • Transdermal spray
  • Jet injector

  • (into tissue/blood)
    Skin (transdermal)
  • Intradermal
  • Subcutaneous
  • Transdermal implant
  • Organs
    Central nervous system
    Circulatory,
    musculoskeletal
    Routes of administration, dosage forms
    Oral
    Digestive tract (enteral)
    Solids
    Liquids
    Oral mucosa (buccal, sublabial, sublingual)
    Solids
    Liquids
    Respiratory tract (inhalation)
    Solids
    0
    0
    Liquids
    Gas
    Ophthalmic,
    otic, nasal
    Urogenital
  • Ointment
  • Pessary
  • Vaginal ring
  • Douche
  • Intrauterine device (IUD)
  • Extra-amniotic infusion
  • Intravesical infusion
  • Rectal (enteral)
    Dermal (topical)
  • Ointment
  • Topical cream
  • Topical gel
  • Liniment
  • Paste
  • Film
  • DMSO solution
  • Iontophoresis
  • Hydrogel
  • Liposomes
  • Transfersome vesicles
  • Cream
  • Lotion
  • Lip balm
  • Medicated shampoo
  • Dermal patch
  • Transdermal patch
  • Transdermal spray
  • Jet injector

  • (into tissue/blood)
    Skin (transdermal)
  • Intradermal
  • Subcutaneous
  • Transdermal implant
  • Organs
    Central nervous system
    Circulatory,
    musculoskeletal
    Categories: