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This is an old revision of this page, as edited by Doors22 (talk | contribs) at 05:23, 4 March 2015. The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

Finasteride

As I wrote on my talkpage, doi:10.1111/j.1743-6109.2010.02157.x is a reasonable source to support any claims of persistent sexual dysfunction after finasteride use. I suggested, however, that you wait until it has appeared in print so any reactions in the medical literature can be noted. I would also strongly suggest that you tone down the language of your addition; I can't see any evidence that there is a "controversy" here, for instance. Instead, I would integrate this information into the current "side-effects" section.

Misplaced Pages has a guideline for additions to medical articles, WP:MEDRS. Could I urge you to read through this document, because if you follow its advice your edits are more likely not to be reverted. JFW | T@lk 19:54, 7 February 2011 (UTC)

September 2012

You can't expect other people not to edit the article, as you appear to say here. Misplaced Pages is the encyclopedia anyone can edit. Biosthmors (talk) 02:11, 27 September 2012 (UTC)

See Misplaced Pages:Notability (organizations and companies) if you want to try and create an article on the organization itself. Best. Biosthmors (talk) 16:48, 27 September 2012 (UTC)

Sockpuppetry case

Your name has been mentioned in connection with a sockpuppetry case. Please refer to Misplaced Pages:Sockpuppet investigations/Brainbug666 for evidence. Please make sure you make yourself familiar with the guide to responding to cases before editing the evidence page. Stalwart111 (talk) 23:35, 4 October 2012 (UTC)

Talkback

Jackmcbarn (talk) 17:46, 7 August 2013 (UTC)

February 2014

Hello, I'm Puffin. I noticed that you recently removed some content from Finasteride, with this edit, without explaining why. In the future, it would be helpful to others if you described your changes to Misplaced Pages with an edit summary. If this was a mistake, don't worry, the removed content has been restored. If you think I made a mistake, or if you have any questions, you can leave me a message on my talk page. Thanks. Puffin 20:10, 22 February 2014 (UTC)

Finasteride Sept 28

I am having technical problems with the Finasteride Talk page, so am temporarily placing my explanation of my edits here.

Several changes made on September 11 were reverted with the explanation "Please don't remove sections that have been discussed and agreed upon months/years earlier - Discuss further on talk page if you wish)". First I'd say that I don't see anything on the Talk page clearly indicating that the language you have reverted back to is "consensus". The discussion ended on February 24, with me asking you a series of questions that you never responded to.

• "In December 2008, the Swedish Medical Products agency concluded a safety investigation of finasteride and advised that finasteride may cause irreversible sexual dysfunction. The Agency's updated safety information lists difficulty in obtaining an erection that persists indefinitely, even after the discontinuation of finasteride, as a possible side effect of the drug"

As my edit summary explains, the quoted insert only says that there have been case reports and causation is unestablished. It is WP:UNDUE to call this a "warning". I've literally come across AERS reports in which people have reported "death of pet" as a side effect of medication. If we included every spontaneous adverse event report as a "warning" for other drugs we'd need several hundred thousand KB just to list them out. This is not meaningful evidence in support of a causative relationship. Furthermore, the link does not work, making this claim unverifiable and subject to immediate removal under WP:VERIFY

• "The UK's Medical and Healthcare Products Regulatory Agency (MHRA) cites reports of erectile dysfunction that persists once use of finasteride has stoppedIn April 2011 Merck revised the United States' warning in consumer and medical leaflets to include erectile dysfunction that may persist after stopping finasteride."

As noted in my edit summary, the cited document from MHRA appears to say nothing about sexual dysfunction. Being unverifiable, it is subject to immediate deletion per WP:VERIFY. You've restored this material without addressing my explanation for the edit, and in contrast to your comment, there is no consensus on the Talk page for including this material. Even if there were, it would violate WP:CONEXCEPT as the material is unverifiable.

• In April 2012, the warning label was further strengthened to include reports of persistent libido disorders, ejaculation disorders, orgasm disorders, and decreased libido. According to FDA, these warnings were added as precaution after reviewing 678 case reports of post-treatment sexual dysfunction received over an 18 year period. The Agency further stated that "despite the fact that clear causal links between finasteride (Propecia and Proscar) and sexual adverse events have NOT been established, the cases suggest a broader range of adverse effects than previously reported in patients taking these drugs."

This is probably an acceptable source as the FDA issued a release around the label changes.

I've deleted the Swedish Medical Agency and MHRA references and left the FDA one in place.

• "regulatory authorities have listed mood disorders as among the possible adverse effects of finasteride,"

As I noted in my edit summary, the cited reference does not support the statement "regulatory authorities have listed mood disorders as among the possible adverse effects of finasteride". You reverted my deletion of this material without commenting on the reason for the deletion. "Prior Consensus", which I see no evidence for on the Talk page, is insufficient to overcome the fundamental pillar of Misplaced Pages that all content must be sourced.

I've deleted the reference to "regulatory authorities" as unverifiable.

• "Some studies have shown that the dose of finasteride needed to treat male pattern baldness may be smaller than 1 mg. Petitions to the FDA to re-examine the approved dosage in light of the statistical evidence and possible long-term risks, were met with the response that a study had shown increased effect of a 1 mg dose compared to 0.2 mg without added risks; the same study also concluded that doses of 0.01 mg per day were found to be ineffective in treating hair loss."

Once again you've reverted me without responding to the reasons in my edit summary and appealing to a "consensus" for which there is no evidence on the Talk page. As I noted in the edit summary, this petition is non-notable. I could write a petition to the FDA tomorrow requesting that they re-examine the dosage for Lipitor. But I am not a well known expert in the field of cardiology, so its really not notable unless the FDA actually acts on it.

The statement that doses needed may be less than 1 mg cites an FDA document, in which I can find no discussion of dosing issues. Like any other statement without verifiable sources, it can and should be deleted. Verifiability is one of the 3 pillars of Misplaced Pages. I've deleted the paragraph. Formerly 98 (talk) 11:10, 28 September 2014 (UTC)

Your recent edits

Hello and welcome to Misplaced Pages. When you add content to talk pages and Misplaced Pages pages that have open discussion (but never when editing articles), please be sure to sign your posts. There are two ways to do this. Either:

1. Add four tildes ( ~~~~ ) at the end of your comment; or
2. With the cursor positioned at the end of your comment, click on the signature button ( or ) located above the edit window.

This will automatically insert a signature with your username or IP address and the time you posted the comment. This information is necessary to allow other editors to easily see who wrote what and when.

Thank you. --SineBot (talk) 02:16, 14 January 2015 (UTC)

ANI

Just to let you know that I proposed a 1 week block for you for retaliatory editing. Formerly 98 (talk) 05:09, 4 March 2015 (UTC)

Thanks for the good laugh. I hope you are able to see the irony in proposing a ban for retaliatory editing (from many months ago) just because I contributed to the incident that was raised about you on the administrator's noticeboard. I wish you the best of luck with that. Doors22 (talk) 05:23, 4 March 2015 (UTC)