| Revision as of 17:25, 16 February 2012 editBeetstra (talk | contribs)Edit filter managers, Administrators172,084 edits Saving copy of the {{drugbox}} taken from revid 449582668 of page 2-Methyl-5-hydroxytryptamine for the Chem/Drugbox validation project (updated: 'CAS_number'). |
Latest revision as of 16:26, 21 October 2024 edit JWBE (talk | contribs)Extended confirmed users10,129 edits removed Category:Phenols; added Category:Hydroxyarenes using HotCat |
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{{Short description|Chemical compound}} |
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{{ambox | text = This page contains a copy of the infobox ({{tl|drugbox}}) taken from revid of page ] with values updated to verified values.}} |
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{{Infobox drug |
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{{Drugbox |
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| Verifiedfields = changed |
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| verifiedrevid = 443314885 |
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| verifiedrevid = 477214316 |
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| IUPAC_name = 3-(2-aminoethyl)-2-methyl-1''H''-indol-5-ol |
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| IUPAC_name = 3-(2-aminoethyl)-2-methyl-1''H''-indol-5-ol |
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| image = 2-Methyl-5-hydroxytryptamine.png |
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| image = 2-Methyl-5-hydroxytryptamine.svg |
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| image2 = 2-Methyl-5-hydroxytryptamine.gif |
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| image2 = 2-Methyl-5-hydroxytryptamine_-_2.png |
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<!--Clinical data--> |
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<!--Clinical data--> |
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| tradename = |
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| tradename = |
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<!--Identifiers--> |
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<!--Identifiers--> |
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| CAS_number_Ref = {{cascite|changed|??}} |
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| CAS_number = <!-- blanked - oldvalue: 78263-90-8 --> |
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| CAS_number = 78263-90-8 |
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| PubChem = 1574 |
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| PubChem = 1574 |
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| IUPHAR_ligand = 218 |
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| IUPHAR_ligand = 218 |
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<!--Chemical data--> |
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<!--Chemical data--> |
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| C=11 | H=14 | N=2 | O=1 |
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| C=11 | H=14 | N=2 | O=1 |
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⚫ |
| smiles = Oc1cc2c(cc1)c(c2CCN)C |
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| molecular_weight = 190.242 g/mol |
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| smiles = Oc1cc2c(cc1)nc(c2CCN)C |
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| InChI = 1/C11H14N2O/c1-7-9(4-5-12)10-6-8(14)2-3-11(10)13-7/h2-3,6,13-14H,4-5,12H2,1H3 |
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| InChIKey = WYWNEDARFVJQSG-UHFFFAOYAB |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChI = 1S/C11H14N2O/c1-7-9(4-5-12)10-6-8(14)2-3-11(10)13-7/h2-3,6,13-14H,4-5,12H2,1H3 |
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| StdInChI = 1S/C11H14N2O/c1-7-9(4-5-12)10-6-8(14)2-3-11(10)13-7/h2-3,6,13-14H,4-5,12H2,1H3 |
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| StdInChIKey = WYWNEDARFVJQSG-UHFFFAOYSA-N |
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| StdInChIKey = WYWNEDARFVJQSG-UHFFFAOYSA-N |
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}} |
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}} |
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'''2-Methyl-5-hydroxytryptamine''' ('''2-Methylserotonin''', '''2-Methyl-5-HT''') is a ] ] closely related to the ] ] which acts as a moderately ] ] at the ].<ref name="pmid8274071">{{cite journal | doi = 10.1002/ardp.19933261110 |vauthors=Elz S, Zimmermann H, Rehse K | title = Selectivity of sterically fixed tryptamine and 5-methoxytryptamine derivatives for serotonin receptor subtypes, II: Structure-activity relationships and in vitro pharmacology of N-alkyl- and N,N-dialkyl-3- indolylbicyclo--heptane-2-amines. | journal = Archiv der Pharmazie | volume = 326 | issue = 11 | pages = 893–899 | year = 1993 | pmid = 8274071 |s2cid=1671270 }}</ref><ref name="pmid2402303">{{cite journal |vauthors=Craig DA, Eglen RM, Walsh LK, Perkins LA, Whiting RL, Clarke DE | title = 5-Methoxytryptamine and 2-methyl-5-hydroxytryptamine-induced desensitization as a discriminative tool for the 5-HT3 and putative 5-HT4 receptors in guinea pig ileum. | journal = Naunyn-Schmiedeberg's Arch Pharmacol | volume = 342 | issue = 1 | pages = 9–16 | year = 1990 | pmid = 2402303 | doi=10.1007/bf00178965| s2cid = 24743785 }}</ref><ref name="urlSerotonin Receptor Subtypes and Ligands">{{cite web | url = http://www.acnp.org/g4/GN401000039/Ch039.html | title = Serotonin Receptor Subtypes and Ligands | access-date = 2008-04-11 |vauthors=Glennon RA, Dukat M, Westkaemper RB | date = 2000-01-01 | publisher = American College of Neurophyscopharmacology | archive-url= https://web.archive.org/web/20080421160353/http://www.acnp.org/g4/GN401000039/Ch039.html| archive-date= 21 April 2008 <!--DASHBot-->| url-status=live}}</ref> |
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== See also == |
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* ] |
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* ] |
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* ] |
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== References == |
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{{reflist}} |
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{{Serotonergics}} |
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{{Tryptamines}} |
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{{DEFAULTSORT:Methyl-5-hydroxytryptamine, 2-}} |
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] |
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] |
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] |
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] |
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{{nervous-system-drug-stub}} |