Revision as of 10:41, 11 February 2011 editBeetstra (talk | contribs)Edit filter managers, Administrators172,084 edits Script assisted update of identifiers from ChemSpider, CommonChemistry and FDA for the Chem/Drugbox validation project - Updated: ChEMBL.← Previous edit |
Latest revision as of 11:24, 23 January 2023 edit undoEntranced98 (talk | contribs)Extended confirmed users, Pending changes reviewers, Rollbackers174,388 edits Importing Wikidata short description: "Chemical compound"Tag: Shortdesc helper |
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{{Short description|Chemical compound}} |
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{{drugbox | verifiedrevid = 399333546 |
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{{Drugbox |
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| verifiedrevid = 413277905 |
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| IUPAC_name = 2-(5-methoxy-2-methyl-H-indol-3-yl)-N,N-dimethylethanamine |
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| IUPAC_name = 2-(5-methoxy-2-methyl-H-indol-3-yl)-N,N-dimethylethanamine |
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| image = 5-MeO-2,N,N-TMT.svg |
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| image = 5-MeO-2,N,N-TMT.svg |
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| width = 200 |
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| width = 200 |
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<!--Clinical data--> |
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| tradename = |
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| pregnancy_AU = |
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| pregnancy_US = |
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| pregnancy_category = |
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| legal_AU = |
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| legal_CA = |
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| legal_DE = NpSG |
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| legal_UK = Class A |
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| legal_US = |
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| legal_status = |
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| routes_of_administration = |
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<!--Pharmacokinetic data--> |
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| bioavailability = |
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| protein_bound = |
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| metabolism = |
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<!--Identifiers--> |
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| CAS_number = 67292-68-6 |
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| UNII_Ref = {{fdacite|correct|FDA}} |
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| UNII = XZ2CCP18I2 |
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| ATC_prefix = |
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| ATC_suffix = |
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| PubChem = 49756 |
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID = 45143 |
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| ChemSpiderID = 45143 |
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| ChEMBL_Ref = {{ebicite|correct|EBI}} |
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| InChI = 1/C14H20N2O/c1-10-12(7-8-16(2)3)13-9-11(17-4)5-6-14(13)15-10/h5-6,9,15H,7-8H2,1-4H3 |
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| InChIKey = ACEHBQPPDDGCGZ-UHFFFAOYAA |
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| smiles1 = O(c1cc2c(cc1)nc(c2CCN(C)C)C)C |
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| ChEMBL = 7143 |
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| ChEMBL = 7143 |
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<!--Chemical data--> |
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| C=14 | H=20 | N=2 | O=1 |
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| smiles = CC1=C(C2=C(N1)C=CC(=C2)OC)CCN(C)C |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChI = 1S/C14H20N2O/c1-10-12(7-8-16(2)3)13-9-11(17-4)5-6-14(13)15-10/h5-6,9,15H,7-8H2,1-4H3 |
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| StdInChI = 1S/C14H20N2O/c1-10-12(7-8-16(2)3)13-9-11(17-4)5-6-14(13)15-10/h5-6,9,15H,7-8H2,1-4H3 |
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| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChIKey = ACEHBQPPDDGCGZ-UHFFFAOYSA-N |
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| StdInChIKey = ACEHBQPPDDGCGZ-UHFFFAOYSA-N |
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| melting_point = |
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| CAS_number = 67292-68-6 |
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| ATC_suffix = |
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| PubChem = 49756 |
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| C=14 | H=20 | N=2 | O=1 |
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| molecular_weight = 232.321 g/mol |
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| smiles = CC1=C(C2=C(N1)C=CC(=C2)OC)CCN(C)C |
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| pregnancy_US = |
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| legal_AU = |
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}} |
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}} |
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'''5-Methoxy-2,''N'',''N''-trimethyltryptamine''' ('''5-MeO-2,''N'',''N''-TMT''', '''5-MeO-TMT''') is a ] of the ] ] which acts as a ]. It was first ] by ] and reported in his book ] ("Tryptamines i Have Known And Loved").<ref></ref> 5-MeO-TMT is claimed to show psychoactive effects at a dosage of 75-150 mg orally, but these are relatively mild compared to those of other similar ]s. This suggests that while the ] ] on the 2-position of the ] has impaired the ] of ] ]s like ] (MAO), it is also interfering with binding to and/or activation of the ] ] ], the target responsible for mediating the ]ic effects of such compounds. |
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'''5-Methoxy-2,''N'',''N''-trimethyltryptamine''' ('''5-MeO-2,''N'',''N''-TMT''', '''5-MeO-TMT''') is a ] of the ] ] which acts as a ]. It was first ] by ] and reported in his book ] ("Tryptamines i Have Known And Loved").<ref></ref> 5-MeO-TMT is claimed to show psychoactive effects at a dosage of 75–150 mg orally, but these are relatively mild compared to those of other similar ]s. This suggests that while the ] ] on the 2-position of the ] has impaired the ] of ] ]s like ] (MAO), it is also interfering with binding to and/or activation of the ] ] ], the target responsible for mediating the ]ic effects of such compounds. |
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== See also == |
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== See also == |
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{{Tryptamines}} |
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{{Tryptamines}} |
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{{Hallucinogenic tryptamines}} |
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{{Hallucinogenic tryptamines}} |
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{{TiHKAL}} |
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{{DEFAULTSORT:5-Methoxy-2,N,N-Trimethyltryptamine}} |
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{{DEFAULTSORT:5-Methoxy-2, N, N-Trimethyltryptamine}} |
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