Revision as of 18:36, 16 February 2012 editBeetstra (talk | contribs)Edit filter managers, Administrators172,084 edits Saving copy of the {{drugbox}} taken from revid 451225832 of page 6-CAT for the Chem/Drugbox validation project (updated: 'StdInChI'). |
Latest revision as of 08:34, 11 September 2023 edit 0dorkmann (talk | contribs)261 edits cat |
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{{Short description|Chemical compound}} |
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{{ambox | text = This page contains a copy of the infobox ({{tl|drugbox}}) taken from revid of page ] with values updated to verified values.}} |
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{{Drugbox |
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{{Drugbox |
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| Watchedfields = changed |
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| Watchedfields = changed |
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| verifiedrevid = 407705168 |
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| verifiedrevid = 477225729 |
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| IUPAC_name = 6-chloro-2-aminotetralin |
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| IUPAC_name = 6-Chloro-1,2,3,4-tetrahydronaphtalen-2-amine |
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| image = 6-Chloro-2-aminotetralin.svg |
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| image = 6-Chloro-2-aminotetralin.svg |
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<!--Identifiers--> |
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<!--Identifiers--> |
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| CAS_number = 60480-00-4 |
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID = 11269876 |
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| ChemSpiderID = 11269876 |
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| PubChem = 16244336 |
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<!--Chemical data--> |
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<!--Chemical data--> |
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| smiles = C1CC2=C(CC1N)C=CC(=C2)Cl |
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| InChI = 1/C10H12ClN/c11-9-3-1-8-6-10(12)4-2-7(8)5-9/h1,3,5,10H,2,4,6,12H2 |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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| InChIKey = CJRJTCMSQLEPFQ-UHFFFAOYAC |
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| StdInChI_Ref = {{stdinchicite|changed|chemspider}} |
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| StdInChI = 1S/C10H12ClN/c11-9-3-1-8-6-10(12)4-2-7(8)5-9/h1,3,5,10H,2,4,6,12H2 |
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| StdInChI = 1S/C10H12ClN/c11-9-3-1-8-6-10(12)4-2-7(8)5-9/h1,3,5,10H,2,4,6,12H2 |
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| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChIKey = CJRJTCMSQLEPFQ-UHFFFAOYSA-N |
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| StdInChIKey = CJRJTCMSQLEPFQ-UHFFFAOYSA-N |
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}} |
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}} |
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'''6-Chloro-2-aminotetralin''' ('''6-CAT''') is a ] which acts as a ] (SSRA) and is a putative ] in humans.<ref name="pmid4455127">{{cite journal | vauthors = Fuller RW, Perry KW, Baker JC, Molloy BB | title = 6-Chloro-2-aminotetralin, a rigid Conformational analog of 4-chloroamphetamine: pharmacologic properties of it and related compounds in rats | journal = Archives Internationales de Pharmacodynamie et de Therapie | volume = 212 | issue = 1 | pages = 141–53 | date = November 1974 | pmid = 4455127 }}</ref><ref>{{cite journal | vauthors = Fuller RW, Wong DT, Snoddy HD, Bymaster FP | title = Comparison of the effects of 6-chloro-2-aminotetralin and of ORG 6582, a related chloroamphetamine analog, on brain serotonin metabolism in rats | journal = Biochemical Pharmacology | volume = 26 | issue = 1 | pages = 1,333–1,337 | year = 1977 | doi=10.1016/0006-2952(77)90094-6}}</ref> It is a rigid ] of ] (PCA).<ref name="pmid4455127"/> |
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According to Nichols ''et al.'',<ref>{{cite journal | vauthors = Johnson MP, Frescas SP, Oberlender R, Nichols DE | title = Synthesis and pharmacological examination of 1-(3-methoxy-4-methylphenyl)-2-aminopropane and 5-methoxy-6-methyl-2-aminoindan: similarities to 3,4-(methylenedioxy)methamphetamine (MDMA) | journal = Journal of Medicinal Chemistry | volume = 34 | issue = 5 | pages = 1662–8 | date = May 1991 | pmid = 1674539 | doi = 10.1021/jm00109a020 }}</ref> 6-CAT is a non-neurotoxic analog of ]. |
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== See also == |
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* ] |
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== References == |
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{{Reflist}} |
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{{Entactogens|state=expanded}} |
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{{Monoamine releasing agents}} |
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{{DEFAULTSORT:Chloroaminotetralin}} |
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] |
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] |
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] |
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] |