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{{Short description|Chemical compound}} |
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{{one source|date=August 2014}} |
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{{Drugbox |
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{{Drugbox |
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| Verifiedfields = changed |
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| verifiedrevid = 442309649 |
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| verifiedrevid = 447729255 |
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| image = Mertansine mab structure.svg |
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| image = Mertansine mab structure.svg |
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<!-- Monoclonal antibody data --> |
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<!--Monoclonal antibody data--> |
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| type = mab |
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| type = mab |
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| mab_type = mab |
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| mab_type = mab |
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| source = zu/o |
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| source = zu/o |
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| target = ] v6 |
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| target = ] v6 |
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<!-- Clinical data --> |
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| tradename = |
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<!--Clinical data--> |
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| tradename = |
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| pregnancy_AU = |
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| pregnancy_AU = |
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| pregnancy_US = |
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| pregnancy_category = |
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| pregnancy_US = |
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| legal_AU = |
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| pregnancy_category = |
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| legal_AU = |
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| legal_CA = |
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| legal_CA = |
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| legal_UK = |
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| legal_UK = |
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| legal_US = |
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| legal_US = |
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| legal_status = |
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| routes_of_administration = |
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| legal_status = |
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<!-- Pharmacokinetic data --> |
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| routes_of_administration = |
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| bioavailability = |
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| protein_bound = |
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<!--Pharmacokinetic data--> |
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| metabolism = |
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| bioavailability = |
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| elimination_half-life = |
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| protein_bound = |
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| metabolism = |
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| excretion = |
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<!-- Identifiers --> |
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| elimination_half-life = |
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| CAS_number_Ref = {{cascite|correct|??}} |
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| excretion = |
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| CAS_number = |
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<!--Identifiers--> |
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| CAS_number = |
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| ATC_prefix = none |
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| ATC_prefix = none |
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| ATC_suffix = |
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| ATC_suffix = |
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| PubChem = |
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| PubChem = |
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| DrugBank_Ref = {{drugbankcite|correct|drugbank}} |
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| DrugBank_Ref = {{drugbankcite|correct|drugbank}} |
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| DrugBank = |
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| DrugBank = |
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| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} |
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| ChemSpiderID = none |
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<!--Chemical data--> |
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<!-- Chemical data --> |
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| chemical_formula = |
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| chemical_formula = |
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| molecular_weight = |
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| molecular_weight = |
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}} |
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}} |
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'''Bivatuzumab mertansine''' is a combination of ], a ]d ], and ], a ]. It is designed for the treatment of ].<ref>{{cite journal|doi=10.1158/1078-0432.CCR-06-0910|pmid=17062682|year=2006|last1=Tijink|first1=BM|last2=Buter|first2=J|last3=De Bree|first3=R|last4=Giaccone|first4=G|last5=Lang|first5=MS|last6=Staab|first6=A|last7=Leemans|first7=CR|last8=Van Dongen|first8=GA|title=A phase I dose escalation study with anti-CD44v6 bivatuzumab mertansine in patients with incurable squamous cell carcinoma of the head and neck or esophagus|volume=12|issue=20 Pt 1|pages=6064–72|journal=Clinical cancer research : an official journal of the American Association for Cancer Research}}</ref> |
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'''Bivatuzumab mertansine''' is a combination of ], a ], and ], a ]. It is designed for the treatment of ].<ref>{{cite journal | vauthors = Tijink BM, Buter J, de Bree R, Giaccone G, Lang MS, Staab A, Leemans CR, van Dongen GA | display-authors = 6 | title = A phase I dose escalation study with anti-CD44v6 bivatuzumab mertansine in patients with incurable squamous cell carcinoma of the head and neck or esophagus | journal = Clinical Cancer Research | volume = 12 | issue = 20 Pt 1 | pages = 6064–72 | date = October 2006 | pmid = 17062682 | doi = 10.1158/1078-0432.CCR-06-0910 | doi-access = free }}</ref> |
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==References== |
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== References == |
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{{reflist}} |
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{{reflist}} |
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{{monoclonal-antibody-stub}} |
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{{monoclonal-antibody-stub}} |
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{{antineoplastic-drug-stub}} |