| Revision as of 23:58, 6 August 2011 editBeetstra (talk | contribs)Edit filter managers, Administrators172,031 edits Script assisted update of identifiers for the Chem/Drugbox validation project (updated: 'ChEBI').← Previous edit |
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{{chembox |
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| verifiedrevid = 414034801 |
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| verifiedrevid = 443428002 |
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| ImageFile_Ref = {{chemboximage|correct|??}} |
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| ImageCaption = Chemical diagram |
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| ImageFile = Bromodichloromethane displayed.svg |
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| ImageFile_Ref = {{chemboximage|correct|??}} |
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| ImageCaption1 = Spacefill model |
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| IUPACName = Bromodichloromethane |
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| ImageFile = Bromodichloromethane displayed.svg |
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| OtherNames = dichlorobromomethane |
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| ImageFile1 = Bromodichloromethane pubchem spacefill model.png |
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| Section1 = {{Chembox Identifiers |
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| PIN = Bromo(dichloro)methane <!-- Parentheses are used according to Subsection P-16.5.1.3 of Nomenclature of Organic Chemistry – IUPAC Recommendations and Preferred Names 2013 (Blue Book) --> |
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| OtherNames = Bromodichloromethane<br />Dichlorobromomethane |
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| Section1 = {{Chembox Identifiers |
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID = 6119 |
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| ChemSpiderID = 6119 |
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| KEGG_Ref = {{keggcite|correct|kegg}} |
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| KEGG_Ref = {{keggcite|correct|kegg}} |
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| StdInChIKey = FMWLUWPQPKEARP-UHFFFAOYSA-N |
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| StdInChIKey = FMWLUWPQPKEARP-UHFFFAOYSA-N |
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| CASNo = 75-27-4 |
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| CASNo = 75-27-4 |
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| CASNo_Ref = {{cascite|correct|CAS}} |
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| CASNo_Ref = {{cascite|correct|CAS}} |
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| EINECS = 200-856-7 |
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| EINECS = 200-856-7 |
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| RTECS = PA5310000 |
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| RTECS = PA5310000 |
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| PubChem = 6359 |
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| PubChem = 6359 |
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| ChEBI = 34591 |
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| Gmelin = 25941 |
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| Beilstein = 1697005 |
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| UNNumber = 2810 3082 |
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| UNII = 7LN464CH2O |
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| ChEBI_Ref = {{ebicite|correct|EBI}} |
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| ChEBI = 34591 |
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| SMILES = BrC(Cl)Cl |
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| SMILES = BrC(Cl)Cl |
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| InChI = 1/CHBrCl2/c2-1(3)4/h1H |
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| InChI = 1/CHBrCl2/c2-1(3)4/h1H |
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| Section2 = {{Chembox Properties |
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| Section2 = {{Chembox Properties |
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| Formula = CHBrCl<sub>2</sub> |
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| Formula = CHBrCl<sub>2</sub> |
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| MolarMass = 163.8 g/mol |
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| MolarMass = 163.8 g/mol |
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| Appearance = Colorless liquid |
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| Appearance = Colorless liquid |
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| Density = 1.980 g/cm<sup>3</sup> |
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| Density = 1.980 g/cm<sup>3</sup> |
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| MeltingPt = -57 °C |
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| MeltingPtC = -57 |
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| MeltingPt_notes = |
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| BoilingPt = 90 °C |
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| BoilingPtC = 90 |
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| Solubility = 4.5 g/l at 20 °C |
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| RefractIndex = 1.4964 |
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| Section7 = {{Chembox Hazards |
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| Solubility = 4.5 g/L at 20 °C |
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| MainHazards = |
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| MagSus = -66.3·10<sup>−6</sup> cm<sup>3</sup>/mol |
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| RPhrases = {{R45}} {{R46}} {{R20/21/22}} {{R36/37/38}} |
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| SPhrases = {{S45}} {{S26}} {{S28}} {{S27}} {{S36/37/39}} |
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| FlashPt = |
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| Section7 = {{Chembox Hazards |
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| GHSPictograms = {{GHS07}}{{GHS08}} |
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| GHSSignalWord = Danger |
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| HPhrases = {{H-phrases|302|315|319|335|350}} |
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| PPhrases = {{P-phrases|201|202|261|264|270|271|280|281|301+312|302+352|304+340|305+351+338|308+313|312|321|330|332+313|337+313|362|403+233|405|501}} |
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| FlashPt = |
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'''Bromodichloromethane''' is a ] with ] {{chem2|CHBrCl2|auto=1}}. It is a colorless, nonflammable liquid which will dissolve in water, or evaporate in air.<ref name=":0">{{Cite web |title=ToxFAQs™: Bromodichloromethane |url=https://wwwn.cdc.gov/TSP/ToxFAQs/ToxFAQsDetails.aspx?faqid=707&toxid=127 |access-date=2024-08-13 |website=Agency for Toxic Substances and Disease Registry |publisher=]}}</ref> Most of the chemical is produced through the ],<ref name=":0" /> and as a result it can occur in municipally-treated drinking water.<ref>Agency for Toxic Substances & Disease Registry, Accessed 07/10/2012, https://wwwn.cdc.gov/TSP/ToxFAQs/ToxFAQsLanding.aspx?id=707&tid=127</ref> It is also produced in small quantities by algae in the oceans.<ref name=":0" /> According to the CDC, levels normal in drinking water are not known to cause health problems, but it has been classified by the ] as a probable human carcinogen. |
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'''Bromodichloromethane''' is a ] with formula CHBrCl<sub>2</sub>. |
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Bromodichloromethane has formerly been used as a ], and a ] for ]s and ] and because of its high ] for mineral separation.{{Citation needed|date=August 2024}} Now it is only used as a ] or ] in ].{{Citation needed|date=August 2024}} In the US it is only produced in small quantities, which are used for these chemical reasons.<ref name=":0" /> For example, it can be used to produce ], which is widely used in the production of ].<ref name=":1">{{Cite book |url=https://publications.iarc.fr/Book-And-Report-Series/Iarc-Monographs-On-The-Identification-Of-Carcinogenic-Hazards-To-Humans/Chlorinated-Drinking-water-Chlorination-By-products-Some-Other-Halogenated-Compounds-Cobalt-And-Cobalt-Compounds-1991 |title=Chlorinated Drinking-water; Chlorination By-products; Some Other Halogenated Compounds; Cobalt and Cobalt Compounds: IARC Monographs on the Evaluation of Carcinogenic Risks to Humans Volume 52 |year=1991 |isbn=978-92-832-1252-2 |volume=52 |pages=179–212 |language=en}}</ref> It can be prepared by treating a mixture of ] and ] with ] and ].<ref name=":1" /> |
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It has been formerly used as a flame retardant, solvent for fats and waxes and because of its high density for mineral separation. Now it is only used as a reagent or intermediate in organic chemistry. |
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== Toxicity == |
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According to the CDC, {{As of|2020|lc=y}}, levels that it is normal to be exposed to in drinking water are lower than levels known to cause health problems.<ref name=":0" /> A small number of studies have examined the effects of low levels of bromodichloromethane on people, but most were also exposed to other chemicals, so it may not be the only cause of reported health problems.<ref name=":0" /> Studies in animals with much higher levels of the chemical than what humans are normally exposed to have resulted in health problems.<ref name=":0" /> The effects of the chemical on children are unknown but expected to be the same as on adults.<ref name=":0" /> |
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No standards regulating its presence in drinking water currently exist in the United States, though a limit of 80 ppb exists for the total amount of trihalomethanes in general.<ref>{{Cite web |last=Group |first=Environmental Working |title=EWG's Tap Water Database: Disinfection Byproducts |url=https://www.ewg.org/tapwater/reviewed-disinfection-byproducts.php |access-date=2023-08-08 |website=www.ewg.org |language=en}}</ref> The ] claims that bromodichloromethane can increase cancer risks and cause harm to reproduction, child development, and fetal growth and development in when present in quantities higher than 0.06 parts per billion (ppb).<ref>{{Cite web |last=Group |first=Environmental Working |title=EWG's Tap Water Database: Contaminants in Your Water |url=https://www.ewg.org/tapwater/contaminant.php?contamcode=2943?contamcode=2943 |access-date=2023-08-08 |website=www.ewg.org |language=en}}</ref> This data largely comes from studies reviewed or conducted by the California Office of Environmental Health Hazard Assessment.<ref>{{Cite web |title=Public Health Goals for Trihalomethanes in Drinking Water |url=https://oehha.ca.gov/media/downloads/water/chemicals/phg/thmsphg020720.pdf |access-date=2023-08-08 |website=oehha.ca.gov}}</ref> {{As of|2020}}, the chemical is considered by the ] to be reasonably anticipated to be a human carcinogen, and by the ] (EPA) to be a probable human carcinogen.<ref name=":0" /> |
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==Notes== |
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{{reflist}} |
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==External links== |
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==External links== |
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* {{ICSC|0393|03}} |
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* {{ICSC|0393|03}} |
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{{Halomethanes}} |
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{{Halomethanes}} |
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