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{{Short description|Chemical compound}} |
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{{drugbox |
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{{Drugbox |
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| verifiedrevid = 444283882 |
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| UNII_Ref = {{fdacite|changed|FDA}} |
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| IUPAC_name = (6''R'',7''R'')-7-(amino)-3-sulfanyl)ethenyl]-8-oxo-5-thia-1-azabicyclooct-2-ene-2-carboxylic acid |
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| UNII = 28TV2P33KF |
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| image = Ceftiolene.svg |
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| verifiedrevid = 388427880 |
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| IUPAC_name = (6R,7R)-7-(amino)-3-sulfanyl)ethenyl]-8-oxo-5-thia-1-azabicyclooct-2-ene-2-carboxylic acid |
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<!--Clinical data--> |
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| image = Ceftiolene.png |
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| tradename = |
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| CAS_number = 77360-52-2 |
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| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X --> |
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| CAS_supplemental = |
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| pregnancy_US = <!-- A / B / C / D / X --> |
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| ATC_prefix = none |
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| ATC_suffix = |
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| pregnancy_category = |
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| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled--> |
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| ATC_supplemental = |
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| PubChem = 6537430 |
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| legal_CA = <!-- Schedule I, II, III, IV, V, VI, VII, VIII --> |
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| DrugBank = |
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| legal_UK = <!-- GSL, P, POM, CD, or Class A, B, C --> |
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| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V --> |
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| chemical_formula = |
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| legal_status = |
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| C=20 | H=18 | N=8 | O=8 | S=3 |
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| routes_of_administration = |
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| molecular_weight = 594.60 g/mol |
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| smiles = CON=C(C1=CSC(=N1)N)C(=O)NC2C3N(C2=O)C(=C(CS3)C=CSC4=NNC(=O)C(=O)N4CC=O)C(=O)O |
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<!--Pharmacokinetic data--> |
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| bioavailability = |
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| protein_bound = |
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| bioavailability = |
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| metabolism = |
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| protein_bound = |
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| metabolism = |
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| elimination_half-life = |
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| elimination_half-life = |
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| excretion = |
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| excretion = |
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| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X --> |
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<!--Identifiers--> |
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| pregnancy_US = <!-- A / B / C / D / X --> |
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| CAS_number = 77360-52-2 |
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| pregnancy_category= |
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| ATC_prefix = none |
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| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled--> |
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| ATC_suffix = |
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| legal_CA = <!-- Schedule I, II, III, IV, V, VI, VII, VIII --> |
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| ATC_supplemental = |
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| legal_UK = <!-- GSL, P, POM, CD, or Class A, B, C --> |
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| PubChem = 6537430 |
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| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V --> |
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| DrugBank_Ref = {{drugbankcite|correct|drugbank}} |
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| legal_status = |
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| DrugBank = |
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| routes_of_administration = |
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| ChEBI = 140116 |
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| ChEMBL = 2106102 |
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| UNII_Ref = {{fdacite|correct|FDA}} |
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| UNII = 28TV2P33KF |
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| ChemSpiderID = 5020599 |
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| StdInChI = 1S/C20H18N8O8S3/c1-36-26-10(9-7-39-19(21)22-9)13(30)23-11-15(32)28-12(18(34)35)8(6-38-17(11)28)2-5-37-20-25-24-14(31)16(33)27(20)3-4-29/h2,4-5,7,11,17H,3,6H2,1H3,(H2,21,22)(H,23,30)(H,24,31)(H,34,35)/b5-2+,26-10-/t11-,17-/m1/s1 |
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| StdInChIKey = WJXAHFZIHLTPFR-JLRJEBFFSA-N |
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<!--Chemical data--> |
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| chemical_formula = |
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| C=20 | H=18 | N=8 | O=8 | S=3 |
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| smiles = CON=C(C1=CSC(=N1)N)C(=O)NC2C3N(C2=O)C(=C(CS3)C=CSC4=NNC(=O)C(=O)N4CC=O)C(=O)O |
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}} |
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}} |
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'''Ceftiolene''' (]) is a third-generation ] antibiotic. |
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'''Ceftiolene''' (]) is a third-generation ] antibiotic.<ref>{{cite journal | vauthors = Williamson R, Gutmann L, Kitzis MD, Acar JF | title = An evaluation of the bacteriolytic and biochemical properties of ceftiolene (42980RP) | journal = The Journal of Antimicrobial Chemotherapy | volume = 14 | issue = 6 | pages = 581–93 | date = December 1984 | pmid = 6394571 | doi = 10.1093/jac/14.6.581 }}</ref> |
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== References == |
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{{antibiotic-stub}} |
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{{reflist}} |
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{{CephalosporinAntiBiotics}} |
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{{CephalosporinAntiBiotics}} |
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{{antibiotic-stub}} |
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