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{{short description|Basic dye and is used as a common stain in histology}} |
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{{distinguish|Crystal violet}} |
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{{Chembox |
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{{Chembox |
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| verifiedrevid = 401651628 |
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| verifiedrevid = 428778050 |
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|IUPACName=(9-dimethylamino-10-methyl-benzophenoxazin-5-ylidene)ammonium chloride |
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|IUPACName=(9-dimethylamino-10-methyl-benzophenoxazin-5-ylidene)ammonium chloride |
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|ImageFile=Cresyl violet.svg |
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|ImageFile=Cresyl_violet_in_weigh_boat.jpg |
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|ImageSize=270px |
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|OtherNames= 9-(Dimethylamino)-5-imino-10-methyl-5H-benzo(a)phenoxazine hydrochloride; |
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|ImageAlt = Cresyl violet powder |
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Cresole Violet |
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|ImageFile1=Cresyl violet.svg |
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|OtherNames= 9-(Dimethylamino)-5-imino-10-methyl-5''H''-benzophenoxazine hydrochloride<br>Cresole violet |
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|Section1= {{Chembox Identifiers |
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|Section1= {{Chembox Identifiers |
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| InChIKey = ZHAFUINZIZIXFC-UHFFFAOYAN |
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| InChIKey = ZHAFUINZIZIXFC-UHFFFAOYAN |
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID = 27064 |
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| ChemSpiderID = 27064 |
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| PubChem = 29092 |
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| CASNo = 18472-89-4 |
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| EC_number = 242-356-1 |
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| UNII = 2AB49C465R |
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| ChEBI = 52815 |
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| Beilstein = 3910949 |
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| InChI = 1/C19H17N3O.ClH/c1-11-8-15-17(10-16(11)22(2)3)23-18-9-14(20)12-6-4-5-7-13(12)19(18)21-15;/h4-10,20H,1-3H3;1H |
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| InChI = 1/C19H17N3O.ClH/c1-11-8-15-17(10-16(11)22(2)3)23-18-9-14(20)12-6-4-5-7-13(12)19(18)21-15;/h4-10,20H,1-3H3;1H |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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}} |
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|Section3= {{Chembox Hazards |
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|Section3= {{Chembox Hazards |
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| FlashPt=245.5 °C |
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| FlashPtC = 245.5 |
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'''Cresyl violet''' is an organic ] with the ] C<sub>19</sub>H<sub>18</sub>ClN<sub>3</sub>O. It is used in biology and medicine as a ]. Cresyl violet is an effective and reliable stain used for light microscopy sections. Initially, tissue sections are ‘defatted’ by passing through graded dilutions of ]. Then, rehydrated by passing back through decreasing concentrations of ethanol. Lastly, back into water. The ethanol solutions act to differentiate the stain, causing myelin and other components to lose color whereas ] retain the color. |
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'''Cresyl violet''' is an organic ] with the ] C<sub>19</sub>H<sub>18</sub>ClN<sub>3</sub>O. It is a basic dye and is used as a common ] in ]. |
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==Cresyl violet stain== |
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].]] |
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It is used in biology and medicine as a ]. Cresyl violet is an effective and reliable stain used for light microscopy sections. Initially, tissue sections are "defatted" by passing through graded dilutions of ]. Then, rehydrated by passing back through decreasing concentrations of ethanol. Lastly, back into water. The ethanol solutions act to differentiate the stain, causing myelin and other components to lose color whereas ] retain the color. It is also used to find '']''.<ref>{{cite journal |vauthors=Goggin N, Rowland M, Imrie C, Walsh D, Clyne M, Drumm B |title=Effect of ''Helicobacter pylori'' eradication on the natural history of duodenal ulcer disease |journal=Arch. Dis. Child. |volume=79 |issue=6 |pages=502–5 |year=1998 |pmid=10210995 |doi=10.1136/adc.79.6.502 |pmc=1717771}}</ref> |
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] ]s also take up the stain although not as strongly as '']''-like organisms.<ref>{{cite journal |vauthors=Burnett RA, Brown IL, Findlay J |title=Cresyl fast violet staining method for ''Campylobacter'' like organisms |journal=J. Clin. Pathol. |volume=40 |issue=3 |pages=353 |year=1987 |pmid=2435763 |doi=10.1136/jcp.40.3.353-b |pmc=1140916}} .</ref> |
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{{organic-compound-stub}} |
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Cresyl violet is used to stain ] in red blood corpuscles or for staining of the ] in the ] and ]. It is used to demonstrate the ] substance in the neurons and ]. In this role it is also often used as a ] to ], which stains the ]. |
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==References== |
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] |
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{{reflist}} |
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] |
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{{Stains}} |
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==External links== |
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* - University of Western Australia. |
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] |
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