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Dichloralphenazone: Difference between revisions

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Revision as of 21:03, 30 August 2011 editCheMoBot (talk | contribs)Bots141,565 edits Updating {{drugbox}} (no changed fields - added verified revid - updated 'ChEMBL_Ref', 'ChEBI_Ref', 'ChEBI_Ref') per Chem/Drugbox validation (report errors or bugs)← Previous edit Latest revision as of 10:09, 29 January 2023 edit undoEntranced98 (talk | contribs)Extended confirmed users, Pending changes reviewers, Rollbackers174,413 edits Importing Wikidata short description: "Chemical compound"Tag: Shortdesc helper 
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{{Short description|Chemical compound}}
{{Drugbox {{Drugbox
| Verifiedfields = changed
| verifiedrevid = 443636469
| Watchedfields = changed

| verifiedrevid = 447550756
<!--Combo data--> <!--Combo data-->
| type = combo | type = combo
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| component2 = Chloral hydrate | component2 = Chloral hydrate
| class2 = ] | class2 = ]

<!--Clinical data--> <!--Clinical data-->
| tradename = | tradename =
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| legal_status = | legal_status =
| routes_of_administration = Oral | routes_of_administration = Oral

<!--Identifiers--> <!--Identifiers-->
| CAS_number_Ref = {{cascite|correct|??}}
| CAS_number = 480-30-8 | CAS_number = 480-30-8
| ATC_prefix = N05 | ATC_prefix = N05
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| KEGG_Ref = {{keggcite|correct|kegg}} | KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D03785 | KEGG = D03785

<!--Chemical data--> <!--Chemical data-->
| smiles = ClC(Cl)(Cl)C(O)O.ClC(Cl)(Cl)C(O)O.O=C2\C=C(/N(N2c1ccccc1)C)C
| InChI = 1/C11H12N2O.2C2H3Cl3O2/c1-9-8-11(14)13(12(9)2)10-6-4-3-5-7-10;2*3-2(4,5)1(6)7/h3-8H,1-2H3;2*1,6-7H
| InChIKey = ATKXDQOHNICLQW-UHFFFAOYAV
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C11H12N2O.2C2H3Cl3O2/c1-9-8-11(14)13(12(9)2)10-6-4-3-5-7-10;2*3-2(4,5)1(6)7/h3-8H,1-2H3;2*1,6-7H
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = ATKXDQOHNICLQW-UHFFFAOYSA-N
}} }}
'''Dichloralphenazone''' is a 1:2 mixture of ] with ]. In combination with ] and ], it is the active ingredient of medications for migraine and vascular (tension) headaches, including Epidrin and ]. Performance impairments are common with this drug and caution is advised, for example when driving motor vehicles. Additional uses of dichloralphenazone include sedation for the treatment of short-term ], although there are probably better drug choices for the treatment of insomnia.<ref>{{cite journal | author = Hindmarch I | coauthors = Parrott AC. | year = 1980 | month = | title = The effects of combined sedative and anxiolytic preparations on subjective aspects of sleep and objective measures of arousal and performance the morning following nocturnal medication. I: Acute doses. | journal = Arzneimittelforschung. | volume = 30 | issue = 6 | pages = 1025–8 | pmid = 6106498 }}</ref>


'''Dichloralphenazone''' is a 1:2 mixture of ] with ]. In combination with ] and ], it is the active ingredient of medications for migraine and tension headaches, including '''Epidrin''' and ''']'''. Performance impairments are common with this drug and caution is advised, for example when driving motor vehicles. Additional uses of dichloralphenazone include sedation for the treatment of short-term ], although there are probably better drug choices for the treatment of insomnia.<ref>{{cite journal | vauthors = Hindmarch I, Parrott AC | title = The effects of combined sedative and anxiolytic preparations on subjective aspects of sleep and objective measures of arousal and performance the morning following nocturnal medication. I: Acute doses | journal = Arzneimittel-Forschung | volume = 30 | issue = 6 | pages = 1025–8 | year = 1980 | pmid = 6106498 }}</ref>
==References==
<references/>


==External links== == See also ==
* ]

== References ==
{{Reflist|2}}

== External links ==
* {{ATC|N05|CC04}} * {{ATC|N05|CC04}}


{{Hypnotics and sedatives}} {{Hypnotics and sedatives}}
{{GABAAR PAMs}}

] ]
] ]
] ]
] ]
]


{{sedative-stub}}

{{nervous-system-drug-stub}}
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