| Revision as of 20:05, 16 February 2012 editBeetstra (talk | contribs)Edit filter managers, Administrators172,031 edits Saving copy of the {{drugbox}} taken from revid 457805095 of page Activella for the Chem/Drugbox validation project (updated: 'ChemSpiderID'). |
Latest revision as of 02:56, 18 December 2023 edit OAbot (talk | contribs)Bots441,761 editsm Open access bot: doi updated in citation with #oabot. |
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{{Short description|Pharmaceutical combination}} |
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{{ambox | text = This page contains a copy of the infobox ({{tl|drugbox}}) taken from revid of page ] with values updated to verified values.}} |
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{{Drugbox |
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{{Drugbox |
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| Verifiedfields = changed |
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| Verifiedfields = changed |
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| verifiedrevid = 457803984 |
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| verifiedrevid = 477241732 |
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<!-- Combo data --> |
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| drug_name = Activella |
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<!--Combo data--> |
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| type = combo |
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| type = combo |
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| component1 = Estradiol |
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| component1 = Estradiol |
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| class1 = ] |
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| class1 = ] |
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| component2 = Norethindrone |
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| component2 = Norethisterone acetate |
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| class2 = ] |
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| class2 = ] |
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<!-- Clinical data --> |
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| tradename = Activella, Amabelz, CombiPatch, others |
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<!--Clinical data--> |
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| Drugs.com = {{drugs.com|ppa|estradiol-and-norethindrone.html}} |
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| tradename = |
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| Drugs.com = {{drugs.com|monograph|enablex}} |
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| MedlinePlus = a601041 |
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| MedlinePlus = a601041 |
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| pregnancy_US = X |
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| pregnancy_US = X |
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| legal_US = Rx-only |
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| legal_US = Rx-only |
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| routes_of_administration = By mouth |
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<!--Identifiers--> |
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| ATC_prefix = G03 |
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| ATC_prefix = G03 |
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| ATC_suffix = FA01 |
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| ATC_suffix = FA01 |
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<!-- Identifiers --> |
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| CAS_number_Ref = {{cascite|changed|??}} |
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| CAS_number = 77728-33-7 |
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| CAS_supplemental = |
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| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} |
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| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} |
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| ChemSpiderID = none |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChI = 1S/C22H28O3.C18H24O2/c1-4-22(25-14(2)23)12-10-20-19-7-5-15-13-16(24)6-8-17(15)18(19)9-11-21(20,22)3;1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h1,13,17-20H,5-12H2,2-3H3;3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t17-,18+,19+,20-,21-,22-;14-,15-,16+,17+,18+/m01/s1 |
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| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChIKey = NAUDKYVGHCCLOT-LAQCMFAESA-N |
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| ChemSpiderID = 2308025 |
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}} |
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}} |
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'''Estradiol/norethisterone acetate''' ('''E2/NETA'''), sold under the brand name '''Activella''' among others, is a ] of ] (E2) and ] (NETA) which is used in the treatment of ]s, ], and ]<ref>{{cite journal | vauthors = Morabito N, Crisafulli A, Vergara C, Gaudio A, Lasco A, Frisina N, D'Anna R, Corrado F, Pizzoleo MA, Cincotta M, Altavilla D, Ientile R, Squadrito F | display-authors = 6 | title = Effects of genistein and hormone-replacement therapy on bone loss in early postmenopausal women: a randomized double-blind placebo-controlled study | journal = Journal of Bone and Mineral Research | volume = 17 | issue = 10 | pages = 1904–12 | date = October 2002 | pmid = 12369794 | doi = 10.1359/jbmr.2002.17.10.1904 | s2cid = 29312298 | doi-access = free }}</ref> associated with ].<ref name="CombiPatch-Label">{{cite web | title = CombiPatch (estradiol/norethindrone acetate transdermal system) Prescribing Information | url = https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020870s023lbl.pdf | work = Noven Pharmaceuticals, Inc. | publisher = U.S. Food and Drug Administration }}</ref> Activella specifically is marketed by ] and is supplied as film-coated tablets containing 1 mg estradiol and 0.5 mg norethisterone acetate. '''CombiPatch''' is a combination of estradiol and NETA provided as a ].<ref name="CombiPatch-Label" /> |
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== See also == |
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* ] |
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* ] |
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* ] |
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* ] |
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== References == |
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{{Reflist}} |
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{{Estrogens and antiestrogens}} |
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{{Progestogens and antiprogestogens}} |
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{{Estrogen receptor modulators}} |
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{{Progesterone receptor modulators}} |
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] |
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] |
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{{Genito-urinary-drug-stub}} |