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{{Short description|Chemical compound}}
{{Drugbox {{Drugbox
⚫ | verifiedrevid = 447992218
| Verifiedfields = changed
⚫ | IUPAC_name = Ethyl 1--4-phenylpiperidine-4-carboxylate
| Watchedfields = changed
⚫ | verifiedrevid = 399926227
⚫ | IUPAC_name = ethyl 1--4-phenylpiperidine-4-carboxylate
| image = Etoxeridine.svg | image = Etoxeridine.svg
| width = 160 | width = 160
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| pregnancy_US = <!-- A / B / C / D / X --> | pregnancy_US = <!-- A / B / C / D / X -->
| pregnancy_category = | pregnancy_category =
| legal_AU = <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 --> | legal_AU = S9
| legal_BR = A1
⚫ | legal_CA = <!-- Schedule I -->
| legal_BR_comment = <ref>{{Cite web |author=Anvisa |author-link=Brazilian Health Regulatory Agency |date=2023-03-31 |title=RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial |trans-title=Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control|url=https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-784-de-31-de-marco-de-2023-474904992 |url-status=live |archive-url=https://web.archive.org/web/20230803143925/https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-784-de-31-de-marco-de-2023-474904992 |archive-date=2023-08-03 |access-date=2023-08-16 |publisher=] |language=pt-BR |publication-date=2023-04-04}}</ref>
⚫ | legal_CA = Schedule I
| legal_UK = Class A | legal_UK = Class A
| legal_US = Schedule I | legal_US = Schedule I
| legal_status = | legal_DE = Anlage I


<!--Pharmacokinetic data--> <!--Pharmacokinetic data-->
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| metabolism = | metabolism =
| elimination_half-life = | elimination_half-life =
| excretion = | excretion =


<!--Identifiers--> <!--Identifiers-->
| CAS_number_Ref = {{cascite|correct|??}}
| CAS_number = 469-82-9 | CAS_number = 469-82-9
| ChEMBL = 2104254
| ATC_prefix = none | ATC_prefix = none
| ATC_suffix = | ATC_suffix =
| PubChem = 61122 | PubChem = 61122
| DrugBank_Ref = {{drugbankcite|changed|drugbank}} | DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| DrugBank = DB01505 | DrugBank = DB01505
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 55070 | ChemSpiderID = 55070
| UNII_Ref = {{fdacite|changed|FDA}} | UNII_Ref = {{fdacite|correct|FDA}}
| UNII = RHW35E1G7E | UNII = RHW35E1G7E
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D12680


<!--Chemical data--> <!--Chemical data-->
| C=18 | H=27 | N=1 | O=4 | C=18 | H=27 | N=1 | O=4
| molecular_weight = 321.41 g/mol
| smiles = C1(CCN(CC1)CCOCCO)(C(=O)OCC)C2=CC=CC=C2 | smiles = C1(CCN(CC1)CCOCCO)(C(=O)OCC)C2=CC=CC=C2
| InChI = 1/C18H27NO4/c1-2-23-17(21)18(16-6-4-3-5-7-16)8-10-19(11-9-18)12-14-22-15-13-20/h3-7,20H,2,8-15H2,1H3
| InChIKey = KJTKYGFGPQSRRA-UHFFFAOYAV
| StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C18H27NO4/c1-2-23-17(21)18(16-6-4-3-5-7-16)8-10-19(11-9-18)12-14-22-15-13-20/h3-7,20H,2,8-15H2,1H3 | StdInChI = 1S/C18H27NO4/c1-2-23-17(21)18(16-6-4-3-5-7-16)8-10-19(11-9-18)12-14-22-15-13-20/h3-7,20H,2,8-15H2,1H3
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}} }}


'''Etoxeridine''' ('''Carbetidine''', '''Atenos''') is a 4-]] derivative that is related to the ] ] drug ] (meperidine). '''Etoxeridine''' ('''Carbetidine''', '''Atenos''') is a 4-]] derivative that is related to the clinically used ] ] drug ] (meperidine).

⚫ Etoxeridine was developed in the 1950s and investigated for use in surgical ], however it was never commercialised and is not currently used in medicine.<ref>Merlevede E, Levis S. Pharmacological study of carbetidine, a new synthetic analgesic. (French). ''Archives Internationales de Pharmacodynamie et de Therapie''. 1958 May 1;115(1-2):213-32.</ref><ref>Sironi PG. Brief note on a new synthetic analgesic: carbetidine hydrochloride. (Italian). ''Minerva Anestesiologica''. 1959 Jun;25(6):251-4.</ref><ref>Crawford JS, Foldes FF. Studies on the respiratory and circulatory effects of carbetidine HCI used for supplementation of thiopentone sodium-nitrous oxide-oxygen anaesthesia. ''British Journal of Anaesthesia''. 1959 Aug;31:348-51.</ref>


⚫ Etoxeridine was developed in the 1950s<ref>{{cite patent | country = BE | number = 558883}}</ref> and investigated for use in surgical ], however it was never commercialized and is not currently used in medicine.<ref>{{Cite journal | vauthors = Merlevede E, Levis S | title = Pharmacological study of carbetidine, a new synthetic analgesic | language = French | journal = Archives Internationales de Pharmacodynamie et de Thérapie | date = 1958 | volume = 115 | issue = 1–2 | pages = 213–232| pmid = 13545901 }}</ref><ref>{{Cite journal | author = Sironi PG | title = Brief note on a new synthetic analgesic: carbetidine hydrochloride | language = Italian | journal = Minerva Anestesiologica | date = 1959 | volume = 25 | issue = 6 | pages = 251–254 | pmid = 13674097 }}</ref><ref>{{cite journal | vauthors = Crawford JS, Foldes FF | title = Studies on the respiratory and circulatory effects of carbetidine HCI used for supplementation of thiopentone sodium-nitrous oxide-oxygen anaesthesia | journal = British Journal of Anaesthesia | volume = 31 | issue = 8 | pages = 348–51 | date = August 1959 | pmid = 13812715 | doi = 10.1093/bja/31.8.348 | doi-access = free }}</ref> As with other opioids which were not in clinical use during the drafting of the ], it is categorized as a Schedule I narcotic.


== References == == References ==
{{Reflist|2}}
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{{Opioidergics}}


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