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{{Unreferenced|date=December 2009}} |
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{{Drugbox |
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{{Drugbox |
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| verifiedrevid = 424663728 |
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| verifiedrevid = 447578824 |
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| IUPAC_name = Iron(+3) cation dihydroxide pentasulfate |
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| IUPAC_name = Iron(+3) cation dihydroxide pentasulfate |
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| image = Ferric subsulfate solution.png |
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| image = Ferric subsulfate solution.png |
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<!--Clinical data--> |
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<!--Clinical data--> |
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| tradename = |
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| tradename = |
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| pregnancy_category = |
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| pregnancy_category = |
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| legal_status = |
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| legal_status = |
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| routes_of_administration = ] |
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| routes_of_administration = ] |
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<!--Pharmacokinetic data--> |
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<!--Pharmacokinetic data--> |
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| bioavailability = |
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| bioavailability = |
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| metabolism = |
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| metabolism = |
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| elimination_half-life = |
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| elimination_half-life = |
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| excretion = |
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| excretion = |
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<!--Identifiers--> |
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<!--Identifiers--> |
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| CAS_number_Ref = {{cascite|correct|??}} |
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| CAS_number = 1310-45-8 |
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| CAS_number = 1310-45-8 |
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| UNII_Ref = {{fdacite|correct|FDA}} |
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| UNII = 3QJ8WS6V8H |
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| PubChem = 159372 |
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| PubChem = 159372 |
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| ChemSpiderID = 140157 |
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| smiles = ..S(=O)(=O).S(=O)(=O).S(=O)(=O).S(=O)(=O).S(=O)(=O).... |
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| StdInChI = 1S/4Fe.5H2O4S.2H2O/c;;;;5*1-5(2,3)4;;/h;;;;5*(H2,1,2,3,4);2*1H2/q4*+3;;;;;;;/p-12 |
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| StdInChIKey = GDPKWKCLDUOTMP-UHFFFAOYSA-B |
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<!--Chemical data--> |
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<!--Chemical data--> |
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| H=2 | Fe=4 | O=22 | S=5 |
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| H=2 | Fe=4 | O=22 | S=5 |
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| molecular_weight = 737.713 g/mol |
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'''Ferric subsulfate solution''' is a ] or ] used after superficial skin biopsies. Ferric subsulfate solution is also known as '''Basic Ferric Sulfate Solution''' or '''Monsel's Solution'''. It has a recognised formula published in ] 29. |
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'''Ferric subsulfate solution''' is a ] or ] used after superficial skin biopsies.<ref>{{cite web|title=Ferric Subsulfate|url=https://www.drugs.com/ppa/ferric-subsulfate.html|publisher=Drugs.com}}</ref> Ferric subsulfate solution is also known as '''basic ferric sulfate solution''' or '''Monsel's solution'''. It has a recognised formula published in ] 29. |
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==Active ingredients== |
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==Active ingredients== |
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Ferric subsulfate solution is prepared from ], ] and ]. |
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Ferric subsulfate solution is prepared from ], ] and ]. |
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It contains, per 100 mL, basic ferric sulfate equivalent to not less than 20g and not more than 22g of iron.{{cn|date=September 2023}} |
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It contains, in each 100 mL, basic ferric sulfate equivalent to not less than 20g and not more than 22g of iron. |
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==Storage== |
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==Storage== |
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Ferric subsulfate solution should be stored in airtight containers at a temperature above 22 degrees Celsius. Crystallisation may occur at temperatures below 22 degrees. Warming the solution may redissolve the crystals. The solution should be protected from light. |
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Ferric subsulfate solution is generally stored in airtight containers at a temperature above 22 degrees Celsius. Crystallization may occur at temperatures below 22 degrees. Warming the solution may redissolve the crystals. The solution is typically protected from light.{{cn|date=August 2022}} |
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==Brandnames== |
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==Other uses== |
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Ferric subsulfate (also known as Monsel's solution) is often used by Jewish burial societies (]) to stop post-mortem bleeding. Since Jewish burial does not allow any external skin adhesives such as bandages, tape, glue or resin, ferric subsulfate is an effective way to stop post-mortem bleeding. Most post-mortem bleeding stems from surgery, emergency room situations, autopsies or blood which may result when removing IV lines during Jewish burial preparation. A piece of cotton, or Q-tip, soaked with this solution is pressed against the open wound and held for a few seconds. This is usually enough time for the seal to take effect. For more severe cases, such as arterial lines, if the line is still inside, the solution can be inserted directly into the IV line.<ref>Silver Spring Maryland ] (Jewish Burial Society)</ref> |
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==Brand names== |
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] by ] is a thickened and specially modified gel formulation. |
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] by ] is a thickened and specially modified gel formulation. |
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==History== |
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It was invented in the late 1840s by Leon Monsel (March 13, 1816 – April 15, 1878), a French military pharmacist. His invention soon became a standard in the French Corps, which saved many lives during battles of the French Army.{{Citation needed|date=September 2014}} |
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==References== |
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{{Reflist}} |
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{{DEFAULTSORT:Ferric Subsulfate Solution}} |
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{{DEFAULTSORT:Ferric Subsulfate Solution}} |
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