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{{Short description|Chemical compound}} |
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{{Drugbox |
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{{Drugbox |
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| verifiedrevid = 400110892 |
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| verifiedrevid = 449583191 |
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| IUPAC_name = Sodium 5-ethyl-5-hexyl-4,6-dioxo-1H-pyrimidin-2-olate |
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| IUPAC_name = sodium 5-ethyl-5-hexyl-4,6-dioxo-1H-pyrimidin-2-olate |
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| image = Sodium_Hexethal.svg |
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| image = Sodium_Hexethal.svg |
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| width = 135 |
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<!--Clinical data--> |
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<!--Clinical data--> |
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| pregnancy_category = |
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| pregnancy_category = |
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| legal_AU = <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 --> |
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| legal_AU = <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 --> |
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| legal_CA = <!-- / Schedule I, II, III, IV, V, VI, VII, VIII --> |
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| legal_CA = Schedule IV |
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| legal_UK = <!-- GSL / P / POM / CD / Class A, B, C --> |
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| legal_UK = <!-- GSL / P / POM / CD / Class A, B, C --> |
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| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V --> |
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| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V --> |
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<!--Identifiers--> |
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<!--Identifiers--> |
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| CAS_number_Ref = {{cascite|correct|??}} |
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| CAS_number = 144-00-3 |
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| CAS_number = 144-00-3 |
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| UNII_Ref = {{fdacite|correct|FDA}} |
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| UNII = ATA79U054W |
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| ATC_prefix = none |
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| ATC_prefix = none |
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| ATC_suffix = |
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| ATC_suffix = |
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<!--Chemical data--> |
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<!--Chemical data--> |
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| C=12 | H=19 | N=2 | Na=1 | O=3 |
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| C=12 | H=19 | N=2 | Na=1 | O=3 |
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| molecular_weight = 262.281 g/mol |
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| smiles = .O=C1/N=C(/)NC(=O)C1(CCCCCC)CC |
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| smiles = .O=C1/N=C(/)NC(=O)C1(CCCCCC)CC |
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| InChI = 1/C12H20N2O3.Na/c1-3-5-6-7-8-12(4-2)9(15)13-11(17)14-10(12)16;/h3-8H2,1-2H3,(H2,13,14,15,16,17);/q;+1/p-1 |
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| InChIKey = HXUAXLUDTCGASZ-REWHXWOFAQ |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChI = 1S/C12H20N2O3.Na/c1-3-5-6-7-8-12(4-2)9(15)13-11(17)14-10(12)16;/h3-8H2,1-2H3,(H2,13,14,15,16,17);/q;+1/p-1 |
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| StdInChI = 1S/C12H20N2O3.Na/c1-3-5-6-7-8-12(4-2)9(15)13-11(17)14-10(12)16;/h3-8H2,1-2H3,(H2,13,14,15,16,17);/q;+1/p-1 |
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| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChIKey = HXUAXLUDTCGASZ-UHFFFAOYSA-M |
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| StdInChIKey = HXUAXLUDTCGASZ-UHFFFAOYSA-M |
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| synonyms = Sodium 5-ethyl-5-hexylbarbiturate, Ortol, Hebaral |
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| synonyms = Sodium 5-ethyl-5-hexylbarbiturate, Ortal, Hebaral |
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}} |
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}} |
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'''Hexethal''' ('''Ortol''') is a ] derivative invented in the 1940s. It has ] and ] properties, and was used primarily as an anaesthetic in ] medicine. <ref> Butler TC. The rate of penetration of barbituric acid derivatives into the brain. Journal of Pharmacology And Experimental Therapeutics, 1950. 100(2): 219-226 </ref> Hexethal is considered similar in effects to ], with a very fast onset of action but short duration of effects. |
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'''Hexethal''' ('''Ortal''') is a ] derivative invented in the 1940s. It has ], ], ], and ] properties, and was used primarily as an anaesthetic in ] medicine. |
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<ref>{{cite journal | vauthors = Butler TC | title = The rate of penetration of barbituric acid derivatives into the brain | journal = The Journal of Pharmacology and Experimental Therapeutics | volume = 100 | issue = 2 | pages = 219–26 | date = October 1950 | pmid = 14784958 }}</ref> |
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Hexethal is considered similar in effects to ], with a very fast onset of action but short duration of effects. |
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== References == |
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== References == |
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{{Reflist}} |
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<references /> |
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{{barbiturates}} |
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] |
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{{GABAAR PAMs}} |
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] |
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{{nervous-system-drug-stub}} |
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{{sedative-stub}} |