| Revision as of 01:10, 7 September 2011 editCheMoBot (talk | contribs)Bots141,565 edits Updating {{chembox}} (no changed fields - added verified revid - updated 'DrugBank_Ref', 'ChEMBL_Ref') per Chem/Drugbox validation (report errors or bugs)← Previous edit |
Latest revision as of 10:57, 1 July 2024 edit undoMichael D. Turnbull (talk | contribs)Extended confirmed users13,742 edits WP:BANREVERTTag: Manual revert |
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{{chembox |
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{{Chembox |
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| Verifiedfields = changed |
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| verifiedrevid = 443883203 |
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| Watchedfields = changed |
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| Name = Isobutylamine |
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| verifiedrevid = 448848315 |
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| ImageFile = Isobutylamine.svg |
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| ImageFile = Isobutylamine.svg |
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| ImageName = isobutylamine |
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| ImageFile_Ref = {{chemboximage|correct|??}} |
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| IUPACName = 2-methylpropan-1-amine |
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| ImageSize = 150 |
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| OtherNames = |
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| ImageName1 = Skeletal formula of isobutylamine |
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| Section1 = {{Chembox Identifiers |
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| ImageFile1 = Isobutylamine-3D-balls.png |
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| UNII_Ref = {{fdacite|correct|FDA}} |
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| ImageSize1 = 150 |
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| UNII = 1H60H4LOHZ |
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| PIN = 2-Methylpropan-1-amine |
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| ChEBI_Ref = {{ebicite|correct|EBI}} |
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| OtherNames = (2-Methylpropyl)amine |
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| ChEBI = 15997 |
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|Section1={{Chembox Identifiers |
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| SMILES = NCC(C)C |
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| CASNo = 78-81-9 |
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| CASNo_Ref = {{cascite|correct|CAS}} |
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| PubChem = 6558 |
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| ChemSpiderID = 6310 |
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| ChemSpiderID = 6310 |
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| KEGG_Ref = {{keggcite|correct|kegg}} |
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| UNII_Ref = {{fdacite|correct|FDA}} |
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| UNII = 1H60H4LOHZ |
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| EINECS = 201-145-4 |
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| UNNumber = 1214 |
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| KEGG = C02787 |
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| KEGG = C02787 |
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| KEGG_Ref = {{keggcite|correct|kegg}} |
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| InChI = 1/C4H11N/c1-4(2)3-5/h4H,3,5H2,1-2H3 |
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| MeSHName = isobutylamine |
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| InChIKey = KDSNLYIMUZNERS-UHFFFAOYAP |
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| ChEBI = 15997 |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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| ChEBI_Ref = {{ebicite|correct|EBI}} |
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| RTECS = NP9900000 |
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| Beilstein = 385626 |
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| Gmelin = 81862 |
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| 3DMet = B00498 |
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| SMILES = CC(C)CN |
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| StdInChI = 1S/C4H11N/c1-4(2)3-5/h4H,3,5H2,1-2H3 |
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| StdInChI = 1S/C4H11N/c1-4(2)3-5/h4H,3,5H2,1-2H3 |
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| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChIKey = KDSNLYIMUZNERS-UHFFFAOYSA-N |
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| StdInChIKey = KDSNLYIMUZNERS-UHFFFAOYSA-N |
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| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} |
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| CASNo = 78-81-9 |
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}} |
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| CASNo_Ref = {{cascite|correct|CAS}} |
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|Section2={{Chembox Properties |
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| RTECS = |
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| C = 4 |
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<!--| UNNumber = UN 1125 --> |
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}} |
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| H = 11 |
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| N = 1 |
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| Section2 = {{Chembox Properties |
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| Appearance = Colorless liquid |
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| Formula = C<sub>4</sub>H<sub>11</sub>N |
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| Odor = Fishy, ammoniacal |
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| MolarMass = 73.14 g/mol |
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| Density = 736 mg mL<sup>−1</sup> |
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| Appearance = colorless liquid |
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| MeltingPtK = 186.5 |
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| Density = 0.736 g/cm<sup>3</sup>, liquid |
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| BoilingPtK = 340 to 342 |
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| Solubility = miscible / miscible |
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| Solubility = Miscible |
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| MeltingPt = -72 °C |
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| BoilingPt = 63 °C |
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| RefractIndex = 1.397 |
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<!--| pKa = (Alkaline) 12.5 at 20°C at 100g/l --> |
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| Viscosity = 500 μPa s (at 20 °C) |
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| MagSus = -59.8·10<sup>−6</sup> cm<sup>3</sup>/mol |
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| Viscosity = 0.5 ] at 20 °C |
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}} |
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}} |
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| Section7 = {{Chembox Hazards |
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|Section3={{Chembox Thermochemistry |
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| DeltaHf = −133.0–−132.0 kJ mol<sup>−1</sup> |
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| ExternalMSDS = |
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| DeltaHc = −3.0139–−3.0131 MJ mol<sup>−1</sup> |
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| EUClass = Dangerous for the environment ('''N'''); Highly flammable ('''F+'''); Harmful ('''Xn''') |
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| HeatCapacity = 194 J K<sup>−1</sup> mol<sup>−1</sup> |
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| FlashPt = -19 °C |
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}} |
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| RPhrases = {{R11}} {{R35}} {{R20}} {{R21}} {{R22}} |
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|Section4={{Chembox Hazards |
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| SPhrases = {{S3}} {{S16}} {{S26}} {{S29}} {{S45}} {{S36}} {{S37}} {{S39}} |
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| GHSPictograms = {{GHS flame}} {{GHS corrosion}} {{GHS skull and crossbones}} |
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}} |
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| GHSSignalWord = '''DANGER''' |
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| Section8 = {{Chembox Related |
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| HPhrases = {{H-phrases|225|301|314}} |
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| OtherCpds = ]<br />]<br />]<br />]<br />] |
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| PPhrases = {{P-phrases|210|280|301+310|305+351+338|310}} |
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}} |
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| FlashPtC = −9 |
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| LD50 = 224 mg kg<sup>−1</sup> <small>(oral, rat)</small> |
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}} |
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|Section5={{Chembox Related |
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| OtherFunction_label = alkanamines |
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| OtherFunction = {{Unbulleted list|]|]|]|]|]|]|]|]|]|]}} |
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| OtherCompounds = {{Unbulleted list|]|''N''-Methylisobutylamine}} |
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}} |
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}} |
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}} |
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'''Isobutylamine''' is an organic chemical compound (specifically, an ]) with the formula (CH<sub>3</sub>)<sub>2</sub>CHCH<sub>2</sub>NH<sub>2</sub>, and occurs as a colorless liquid.<ref> chemicalbook.com</ref><ref> Chemblink.com</ref> Isobutylamine is one of the four isomeric amines of ], the others being ], ] and ]. It is the decarboxylated form of the ] ], and the product of the metabolism thereof by the enzyme ]. |
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Isobutylamine is an odorant binding to ] in mice and can trigger sexual behaviour in male mice dependent on the cluster of TAAR2 through TAAR9.<ref name="pmid30158871">{{cite journal | vauthors = Harmeier A, Meyer CA, Staempfli A, Casagrande F, Petrinovic MM, Zhang YP, Künnecke B, Iglesias A, Höner OP, Hoener MC | title = How Female Mice Attract Males: A Urinary Volatile Amine Activates a Trace Amine-Associated Receptor That Induces Male Sexual Interest | journal = Frontiers in Pharmacology | volume = 9 | pages = 924 | date = 2018 | pmid = 30158871 | pmc = 6104183 | doi = 10.3389/fphar.2018.00924 | doi-access = free }}</ref> |
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'''Isobutylamine''' is an organic chemical compound (specifically, an ]) with the formula (CH<sub>3</sub>)<sub>2</sub>CHCH<sub>2</sub>NH<sub>2</sub>, and occurs as a colorless liquid.<ref> chemicalbook.com</ref><ref> Chemblink.com</ref> Isobutylamine is one of the four isomeric amines of ], the others being ], ] and ]. |
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==References== |
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==References== |
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{{reflist}} |
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{{Reflist}} |
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{{amine-stub}} |
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{{Amine-stub}} |
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