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Revision as of 11:41, 12 May 2011 editCheMoBot (talk | contribs)Bots141,565 edits Updating {{chembox}} (no changed fields - added verified revid - updated 'UNII_Ref', 'ChemSpiderID_Ref', 'StdInChI_Ref', 'StdInChIKey_Ref', 'ChEMBL_Ref', 'KEGG_Ref') per Chem/Drugbox validation (← Previous edit Latest revision as of 03:44, 6 May 2023 edit undoLegionMammal978 (talk | contribs)Extended confirmed users7,894 edits add semisystematic name 
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{{chembox {{chembox
| Verifiedfields = changed
⚫ | verifiedrevid = 395738406
| Watchedfields = changed
⚫ | verifiedrevid = 428737673
|ImageFile=Orotidine monophosphate.svg |ImageFile=Orotidine monophosphate.svg
|ImageSize= |ImageSize=
| IUPACName =3-&#8203;-2,6-dioxo-pyrimidine-4-carboxylic acid | IUPACName = 2,6-Dioxo-3-(5-''O''-phosphono-β-<small>D</small>-ribofuranosyl)-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid
| SystematicName = 3-{(2''R'',3''R'',4''S'',5''R'')-3,4-Dihydroxy-6-oxolan-2-yl}-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid
|OtherNames= Orotidylic acid,<br>OMP |OtherNames= Orotidylic acid,<br>OMP
|Section1= {{Chembox Identifiers |Section1= {{Chembox Identifiers
| CASNo_Ref = {{cascite|correct|??}}
| CASNo=2149-82-8 | CASNo=2149-82-8
⚫ | PubChem=968
| UNII_Ref = {{fdacite|correct|FDA}}
⚫ | SMILES= C1=C(N(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)O)O)O)C(=O)O
| UNII = H0ARN8U4Y9
⚫ | MeSHName=Orotidine+5'-monophosphate
⚫ | PubChem = 160617
| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}
| ChemSpiderID = 141140
⚫ | SMILES = c1c(n(c(=O)nc1O)2(((O2)COP(=O)(O)O)O)O)C(=O)O
| InChI = 1/C10H13N2O11P/c13-5-1-3(9(16)17)12(10(18)11-5)8-7(15)6(14)4(23-8)2-22-24(19,20)21/h1,4,6-8,14-15H,2H2,(H,16,17)(H,11,13,18)(H2,19,20,21)/t4-,6-,7-,8-/m1/s1
| InChIKey = KYOBSHFOBAOFBF-XVFCMESIBC
| StdInChI_Ref = {{stdinchicite|changed|chemspider}}
| StdInChI = 1S/C10H13N2O11P/c13-5-1-3(9(16)17)12(10(18)11-5)8-7(15)6(14)4(23-8)2-22-24(19,20)21/h1,4,6-8,14-15H,2H2,(H,16,17)(H,11,13,18)(H2,19,20,21)/t4-,6-,7-,8-/m1/s1
| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}}
| StdInChIKey = KYOBSHFOBAOFBF-XVFCMESISA-N

⚫ | MeSHName=Orotidine+5'-monophosphate
}} }}
|Section2= {{Chembox Properties |Section2= {{Chembox Properties
| Formula=C<sub>10</sub>H<sub>13</sub>N<sub>2</sub>O<sub>11</sub>P | Formula=C<sub>10</sub>H<sub>13</sub>N<sub>2</sub>O<sub>11</sub>P
| MolarMass=368.191 g/mol | MolarMass=368.191 g/mol
| Appearance= | Appearance=
| Density= | Density=
| MeltingPt= | MeltingPt=
| BoilingPt= | BoilingPt=
| Solubility= | Solubility=
}} }}
|Section3= {{Chembox Hazards |Section3= {{Chembox Hazards
| MainHazards= | MainHazards=
| FlashPt= | FlashPt=
| AutoignitionPt=
| Autoignition=
}} }}
}} }}
'''Orotidine 5'-monophosphate''' (OMP), also known as '''orotidylic acid,''' is a ] ] which is the last intermediate in the biosynthesis of ]. OMP is formed from ] and ] by the enzyme ] '''Orotidine 5'-monophosphate''' ('''OMP'''), also known as '''orotidylic acid''', is a ] ]<ref>{{Cite web |last=PubChem |title=Orotidine-5'-monophosphate |url=https://pubchem.ncbi.nlm.nih.gov/compound/160617 |access-date=2023-01-26 |website=pubchem.ncbi.nlm.nih.gov |language=en}}</ref> which is the last intermediate in the biosynthesis of ].<ref name=":0">{{Cite web |title=UMPS uridine monophosphate synthetase - Gene - NCBI |url=https://www.ncbi.nlm.nih.gov/gene?Db=gene&Cmd=ShowDetailView&TermToSearch=7372 |access-date=2023-01-26 |website=www.ncbi.nlm.nih.gov}}</ref> OMP is formed from ] and ] by the enzyme ].


In humans, the enzyme ] converts OMP into ]. If UMP synthase is defective, ] can result. In humans, the enzyme ] converts OMP into ].<ref name=":0" /> If UMP synthase is defective, ] can result.<ref name=":0" />

==References==
{{reflist}}


{{Nucleotide metabolism intermediates}} {{Nucleotide metabolism intermediates}}
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{{biochem-stub}} {{biochem-stub}}

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