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{{Citation style|date=November 2019}} |
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{{No footnotes|date=November 2019}} |
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{{chembox |
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| Verifiedfields = changed |
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| verifiedrevid = 265828401 |
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| Name = Polyethylene glycol |
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| verifiedrevid = 365890277 |
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| ImageFile = Polyethylene glycol.png |
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| ImageName = Polyethylene glycol |
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| Name = Polyethylene glycol |
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| IUPACName = Polyethylene glycol |
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| ImageFile = Poly(ethylene glycol) alternate.svg |
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| ImageName = Polyethylene glycol |
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| Section1 = {{Chembox Identifiers |
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| IUPACName = Polyethylene glycol |
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| CASNo_Ref = {{cascite}} |
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|Section1={{Chembox Identifiers |
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| CASNo = 25322-68-3 |
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| CASNo_Ref = {{cascite|correct|CAS}} |
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| CASNo = 25322-68-3 |
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| UNII_Ref = {{fdacite|correct|FDA}} |
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| UNII = B697894SGQ |
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| Section2 = {{Chembox Properties |
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|Section2={{Chembox Properties |
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| Formula = C<sub>2n</sub>H<sub>4n+2</sub>O<sub>n+1</sub>, n = 8.2 to 9.1 |
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| Formula = C<sub>2n</sub>H<sub>4n+2</sub>O<sub>n+1</sub>, n = 8.2 to 9.1 |
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| MolarMass = 380-420 g/mol |
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| MolarMass = 380-420 g/mol |
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| Density = 1.128 g/cm³ |
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| Density = 1.128 g/cm<sup>3</sup> |
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| Viscosity = 90.0 cSt at 25 °C, 7.3 cSt at 99 °C |
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| Viscosity = 90.0 cSt at 25 °C, 7.3 cSt at 99 °C |
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| MeltingPtC = 4 to 8 |
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| MeltingPt = 4-8 °C |
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| MeltingPt_notes = |
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| FlashPt = 238 °C |
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| FlashPtC = 238 |
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| LD50 = 30 mL/kg, orally in rats |
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| LD50 = 30 mL/kg, orally in rats |
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'''PEG 400''' (polyethylene glycol 400) is a low molecular weight grade of ]. It is a clear, colorless, viscous liquid. Due in part to its low toxicity, PEG 400 is widely used in a variety of pharmaceutical formulations. |
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'''PEG 400''' (polyethylene glycol 400) is a low-molecular-weight grade of ]. It is a clear, colorless, viscous liquid. Due in part to its low toxicity, PEG 400 is widely used in a variety of pharmaceutical formulations. |
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==Chemical properties== |
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==Chemical properties== |
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PEG 400 is strongly ]. The ] of PEG 400 between hexane and water is 0.000015 (log<math>P = -4.8</math>), indicating that when PEG 400 is mixed with water and hexane, there are only 1.5 parts of PEG 400 in the hexane layer per 100,000 parts of PEG 400 in the water layer.<ref>{{cite journal |
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PEG 400 is strongly ]. The ] of PEG 400 between hexane and water is 0.000015 (log<math>P = -4.8</math>), indicating that when PEG 400 is mixed with water and hexane, there are only 15 parts of PEG400 in the hexane layer per 1 million parts of PEG 400 in the water layer.<ref>{{cite journal |
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| title= PEG 400, a hydrophilic molecular probe for measuring intestinal permeability |
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| title = PEG 400, a hydrophilic molecular probe for measuring intestinal permeability |
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| author= T. Y. Ma, D. Hollander, P. Krugliak, K. Katz |
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|author1=T. Y. Ma |author2=D. Hollander |author3=P. Krugliak |author4=K. Katz | journal = Gastroenterology |
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| volume = 98 |
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| journal= Gastroenterology |
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| volume= 98 |
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| issue = 1 |
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| issue= 1 |
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| pages = 39–46 |
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| pages= 39–46 |
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| year = 1990 |
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|doi=10.1016/0016-5085(90)91288-h | url = http://www.gastrojournal.org/article/PII001650859091288H/abstract |
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| year= 1990 |
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| pmid = 2293598}}</ref> |
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| url= http://www.gastrojournal.org/article/PII001650859091288H/abstract |
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| pmid= 2293598}}</ref> |
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PEG 400 is soluble in water, acetone, alcohols, benzene, glycerin, glycols, aromatic hydrocarbons and is slightly soluble in aliphatic hydrocarbons. |
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PEG 400 is soluble in water, acetone, alcohols, benzene, glycerin, glycols, and aromatic hydrocarbons. It is not miscible with aliphatic hydrocarbons nor diethyl ether. Therefore, reaction products can be extracted from the reaction media with those solvents. |
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==References== |
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==References== |