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{{Short description|Chemical compound}} |
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{{unreferenced|date=February 2010}} |
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{{Drugbox |
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{{Drugbox |
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| IUPAC_name = 4-(2-bromo-4,5-dimethoxybenzyl)-4-(2-heptan-2-yl)ethoxy]ethyl)morpholin-4-ium |
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| Watchedfields = changed |
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| image = pinaverium.png |
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| verifiedrevid = 448202349 |
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| CAS_number = 59995-65-2 |
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| IUPAC_name = 4--4-heptanyl)ethoxy]ethyl]morpholin-4-ium bromide |
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| ATC_prefix = A03 |
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| image = pinaverium bromide.svg |
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| ATC_suffix = AX04 |
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| PubChem = 40704 |
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<!--Clinical data--> |
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| DrugBank = |
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| tradename = |
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| C=26|H=41|Br=1|N=1|O=4 |
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| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X --> |
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| molecular_weight = 511.51 g/mol |
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| pregnancy_US = <!-- A / B / C / D / X --> |
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| bioavailability = |
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| pregnancy_category = |
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| protein_bound = |
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| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled--> |
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| metabolism = |
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| legal_CA = <!-- Schedule I, II, III, IV, V, VI, VII, VIII --> |
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| elimination_half-life = |
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| excretion = |
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| legal_UK = <!-- GSL, P, POM, CD, or Class A, B, C --> |
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| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X --> |
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| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V --> |
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| legal_status = |
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| pregnancy_US = <!-- A / B / C / D / X --> |
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| routes_of_administration = |
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| pregnancy_category= |
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| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled--> |
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<!--Pharmacokinetic data--> |
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| legal_CA = <!-- Schedule I, II, III, IV, V, VI, VII, VIII --> |
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| bioavailability = |
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| legal_UK = <!-- GSL, P, POM, CD, or Class A, B, C --> |
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| protein_bound = |
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| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V --> |
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| legal_status = |
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| metabolism = |
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| elimination_half-life = |
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| routes_of_administration = |
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| excretion = |
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<!--Identifiers--> |
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| CAS_number_Ref = {{cascite|correct|CAS}} |
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| CAS_number = 53251-94-8 |
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| UNII_Ref = {{fdacite|changed|FDA}} |
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| UNII = 7SCF54H12J |
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| ATC_prefix = A03 |
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| ATC_suffix = AX04 |
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| PubChem = 40703 |
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| DrugBank_Ref = {{drugbankcite|correct|drugbank}} |
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| DrugBank = DBSALT001130 |
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| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} |
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| ChemSpiderID = 37181 |
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| smiles = CC1(C2CCC(C1C2)CCOCC3(CCOCC3)Cc4cc(c(cc4Br)OC)OC)C. |
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| StdInChI_Ref = {{stdinchicite|changed|chemspider}} |
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| StdInChI = 1S/C26H41BrNO4.BrH/c1-26(2)21-6-5-19(22(26)16-21)7-11-31-12-8-28(9-13-32-14-10-28)18-20-15-24(29-3)25(30-4)17-23(20)27;/h15,17,19,21-22H,5-14,16,18H2,1-4H3;1H/q+1;/p-1 |
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| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}} |
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| StdInChIKey = IKGXLCMLVINENI-UHFFFAOYSA-M |
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<!--Chemical data--> |
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| C=26 | H=41 | Br=2 | N=1 | O=4 |
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'''Pinaverium bromide''' (]) is a medication used for ]s. It belongs to a drug group called ]s and acts as a ] in helping to restore the normal contraction process of the bowel. It is most effective when taken for a full course of treatment and is not designed for immediate symptom relief or sporadic, intermittent use.<ref>{{cite book | vauthors = | chapter = Trimebutine Maleate and Pinaverium Bromide for Irritable Bowel Syndrome: A Review of the Clinical Effectiveness, Safety and Guidelines . | title = CADTH Rapid Response Reports | location = Ottawa (ON) | publisher = Canadian Agency for Drugs and Technologies in Health | date = November 2015 | pmid = 26985535 | chapter-url = https://www.ncbi.nlm.nih.gov/books/NBK350043/ }}</ref> |
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'''Pinaverium''' is a drug used for ]s. It acts as a ]. |
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Pinaverium bromide was first registered in 1975 by ] (now a division of ]), and marketed globally using the brand names '''Dicetel''' and '''Eldicet'''. Generic pinaverium is available in South Korea under a trade name of '''Disten'''<ref>{{cite web | url = http://www.kmle.co.kr/viewDrug.php?m=%B6%F3%BD%C4&inx=26702&c=afdf17b8b3cde357bf3163dd78dbc00f | work = KMLE | title = Drug/Drug Information: Disten Tablet | language = ko | access-date = 2016-03-07 | archive-date = 2018-09-20 | archive-url = https://web.archive.org/web/20180920111710/http://www.kmle.co.kr/viewDrug.php?m=%B6%F3%BD%C4&inx=26702&c=afdf17b8b3cde357bf3163dd78dbc00f | url-status = dead }}</ref> and in Argentina as '''Nulite'''.<ref>{{Cite web | url=http://www.labdominguez.com.ar/es/productos/28-nulite | title=NULITE | work=Laboratorio Dominguez | access-date=2017-07-03 | archive-date=2019-08-24 | archive-url=https://web.archive.org/web/20190824084406/http://www.labdominguez.com.ar/es/productos/28-nulite | url-status=dead }}</ref> |
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==Indications== |
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It is indicated for the treatment and relief of symptoms associated with ] (IBS) including abdominal pain, bowel disturbances and intestinal discomfort; and treatment of symptoms related to functional disorders of biliary tract.<ref>{{Cite book|author=Abbott Laboratories |title=Dicetel Product Insert/Information Malaysia| date=Feb 2012 }}</ref> |
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==References== |
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{{Reflist}} |
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{{Drugs for functional gastrointestinal disorders}} |
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{{Drugs for functional gastrointestinal disorders}} |
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{{gastrointestinal-drug-stub}} |
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