| Revision as of 16:43, 10 August 2011 editBeetstra (talk | contribs)Edit filter managers, Administrators172,031 edits Script assisted update of identifiers for the Chem/Drugbox validation project (updated: 'DrugBank', 'ChEBI').← Previous edit |
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{{Short description|Chemical compound}} |
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{{drugbox |
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{{Distinguish|α-PCyP}} |
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| Verifiedfields = changed |
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{{Drugbox |
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| UNII_Ref = {{fdacite|changed|FDA}} |
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| verifiedrevid = 444089733 |
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| UNII = 183O9O9JE3 |
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| IUPAC_name = 1-(1-phenylcyclohexyl)pyrrolidine |
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| verifiedrevid = 401043924 |
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|IUPAC_name = 1-(1-phenylcyclohexyl)pyrrolidine |
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| image = Rolicyclidine.svg |
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| image = Rolicyclidine.svg |
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| width= 125px |
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| width = 125px |
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<!--Clinical data--> |
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| tradename = |
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| legal_AU = S9 |
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| legal_BR = F2 |
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| legal_BR_comment = <ref>{{Cite web |author=Anvisa |author-link=Brazilian Health Regulatory Agency |date=2023-07-24 |title=RDC Nº 804 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial |trans-title=Collegiate Board Resolution No. 804 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control|url=https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-804-de-24-de-julho-de-2023-498447451 |url-status=live |archive-url=https://web.archive.org/web/20230827163149/https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-804-de-24-de-julho-de-2023-498447451 |archive-date=2023-08-27 |access-date=2023-08-27 |publisher=] |language=pt-BR |publication-date=2023-07-25}}</ref> |
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| legal_CA = Schedule III |
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| legal_UK = Class A |
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| legal_US = Schedule I |
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| legal_DE = Anlage I |
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| legal_UN = P I |
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<!--Identifiers--> |
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| CAS_number = 2201-39-0 |
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| ATC_prefix = none |
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| PubChem = 62436 |
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| DrugBank_Ref = {{drugbankcite|correct|drugbank}} |
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| DrugBank = DB01549 |
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID = 56218 |
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| ChemSpiderID = 56218 |
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| UNII_Ref = {{fdacite|correct|FDA}} |
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| InChI = 1/C16H23N/c1-3-9-15(10-4-1)16(11-5-2-6-12-16)17-13-7-8-14-17/h1,3-4,9-10H,2,5-8,11-14H2 |
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| UNII = 183O9O9JE3 |
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| InChIKey = FYOWWXMGDATDQY-UHFFFAOYAQ |
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| ChEBI_Ref = {{ebicite|correct|EBI}} |
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| ChEBI = 60805 |
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| KEGG_Ref = {{keggcite|correct|kegg}} |
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| KEGG = D12706 |
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<!--Chemical data--> |
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| C=16 | H=23 | N=1 |
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| smiles = c1ccccc1C3(N2CCCC2)CCCCC3 |
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| smiles = c1ccccc1C3(N2CCCC2)CCCCC3 |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChIKey = FYOWWXMGDATDQY-UHFFFAOYSA-N |
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| StdInChIKey = FYOWWXMGDATDQY-UHFFFAOYSA-N |
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| CAS_number= 2201-39-0 |
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| ATC_prefix= none |
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| ATC_suffix= |
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| ChEBI = 60805 |
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| PubChem= 62436 |
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| DrugBank_Ref = {{drugbankcite|correct|drugbank}} |
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| DrugBank = DB01549 |
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| C=16 | H=23 | N=1 |
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| molecular_weight = 229.361 g/mol |
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| bioavailability= |
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| metabolism = |
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| elimination_half-life= |
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| excretion = |
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| pregnancy_category = |
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| legal_status = Schedule I / Class A |
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| routes_of_administration= |
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}} |
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}} |
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'''Rolicyclidine''' ('''PCPy''') is a ] ] drug with ]ic and ] effects. It is similar in effects to ] but is slightly less potent and has less stimulant effects <ref> Kalir A, Edery H, Pelah Z, Balderman D, Porath G. 1-Phenylcycloalkylamine derivatives. II. Synthesis and pharmacological activity. Journal of Medicinal Chemistry. 1969. 12(3):473-477</ref> instead producing a sedative effect described as being somewhat similar to a ], but with additional PCP-like dissociative, anaesthetic and hallucinogenic effects.<ref> DEA Microgram Bulletin, 8, 143, 1975</ref> Due to its similarity in effects to PCP, PCPy was placed into the Schedule I list of illegal drugs in the 1970s, although it has never been widely abused and is now little known. |
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'''Rolicyclidine''' ('''PCPy''') is a ] ] that is similar in effects to ], but is slightly less potent and has fewer stimulant effects.<ref>{{cite journal | vauthors = Kalir A, Edery H, Pelah Z, Balderman D, Porath G | title = 1-Phenycycloalkylamine derivatives. II. Synthesis and pharmacological activity | journal = Journal of Medicinal Chemistry | volume = 12 | issue = 3 | pages = 473–7 | date = May 1969 | pmid = 4977945 | doi = 10.1021/jm00303a030 }}</ref> It instead produces a sedative effect described as being somewhat similar to a ], but with additional PCP-like dissociative, anaesthetic and hallucinogenic effects.<ref>DEA Microgram Bulletin, 8, 143, 1975</ref> Due to its similarity in effects to PCP, PCPy was placed into the Schedule I list of illegal drugs in the 1970s, although it has never been widely abused and is now little known. |
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==See also== |
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==See also== |
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==References== |
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==References== |
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{{Reflist|2}} |
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{{Reflist}} |
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{{General_anesthetics}} |
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{{General_anesthetics}} |
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{{Depressants}} |
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{{Hallucinogens}} |
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{{Hallucinogens}} |
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{{Dopamine receptor modulators}} |
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{{Dopaminergics}} |
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{{Ionotropic glutamate receptor modulators}} |
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{{Glutamatergics}} |
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] |
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] |
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] |
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] |
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{{nervous-system-drug-stub}} |
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{{nervous-system-drug-stub}} |
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] |
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