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4-Thiouridine

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4-Thiouridine
Names
Preferred IUPAC name 1--4-sulfanylidene-3,4-dihydropyrimidin-2(1H)-one
Identifiers
CAS Number
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard 100.034.291 Edit this at Wikidata
EC Number
  • 237-735-3
MeSH Thiouridine
PubChem CID
UNII
CompTox Dashboard (EPA)
InChI
  • InChI=1S/C9H12N2O5S/c12-3-4-6(13)7(14)8(16-4)11-2-1-5(17)10-9(11)15/h1-2,4,6-8,12-14H,3H2,(H,10,15,17)/t4-,6-,7-,8-/m1/s1Key: ZLOIGESWDJYCTF-XVFCMESISA-N
SMILES
  • C1=CN(C(=O)NC1=S)C2C(C(C(O2)CO)O)O
Properties
Chemical formula C9H12N2O5S
Molar mass 260.26 g·mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Infobox references
Chemical compound

4-Thiouridine is an atypical nucleoside formed with the 4-thiouracil base found in transfer RNA (tRNA). Its biosynthesis has been determined.

References

  1. Alberts, Bruce (18 November 2014). Molecular biology of the cell (Sixth ed.). New York, NY. p. 337. ISBN 978-0-8153-4432-2. OCLC 887605755.{{cite book}}: CS1 maint: location missing publisher (link)
  2. Park, Chung-Min; Weerasinghe, Laksiri; Day, Jacob J.; Fukuto, Jon M.; Xian, Ming (2015). "Persulfides: Current knowledge and challenges in chemistry and chemical biology". Molecular BioSystems. 11 (7): 1775–1785. doi:10.1039/c5mb00216h. PMC 4470748. PMID 25969163.


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