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AP3B2
Identifiers
Aliases	AP3B2, NAPTB, adaptor related protein complex 3 beta 2 subunit, EIEE48, adaptor related protein complex 3 subunit beta 2, DEE48
External IDs	OMIM: 602166; MGI: 1100869; HomoloGene: 55837; GeneCards: AP3B2; OMA:AP3B2 - orthologs
Gene location (Mouse) Chr. Chromosome 7 (mouse) Band 7 D3|7 45.71 cM Start 81,110,147 bp End 81,143,673 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in anterior pituitary Brodmann area 10 Brodmann area 9 cingulate gyrus ganglionic eminence Amygdala nucleus accumbens Hypothalamus Region I of hippocampus proper superior frontal gyrus Top expressed in dentate gyrus of hippocampal formation granule cell neural layer of retina visual cortex primary visual cortex superior frontal gyrus cerebellar cortex supraoptic nucleus dorsomedial hypothalamic nucleus central gray substance of midbrain facial motor nucleus More reference expression data BioGPS n/a
Gene ontology Molecular function transporter activity Cellular component AP-3 adaptor complex membrane coat cytoplasmic vesicle clathrin-coated vesicle membrane membrane COPI-coated vesicle axon cytoplasm Golgi apparatus intracellular vesicle Biological process anterograde axonal transport protein transport anterograde synaptic vesicle transport intracellular protein transport vesicle-mediated transport post-Golgi vesicle-mediated transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 8120 11775 Ensembl n/a ENSMUSG00000062444 UniProt Q13367 Q9JME5 RefSeq (mRNA) NM_001278511 NM_001278512 NM_004644 NM_001348440 NM_001348441 NM_021492 NM_146192 RefSeq (protein) NP_001265440 NP_001265441 NP_004635 NP_001335369 NP_001335370 NP_067467 Location (UCSC) n/a Chr 7: 81.11 – 81.14 Mb PubMed search
Wikidata
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AP-3 complex subunit beta-2 is a protein that in humans is encoded by the AP3B2 gene.

References

1. ^ GRCm38: Ensembl release 89: ENSMUSG00000062444 – Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. Newman LS, McKeever MO, Okano HJ, Darnell RB (Oct 1995). "Beta-NAP, a cerebellar degeneration antigen, is a neuron-specific vesicle coat protein". Cell. 82 (5): 773–83. doi:10.1016/0092-8674(95)90474-3. PMID 7671305.
5. Darnell RB, Furneaux HM, Posner JB (Jun 1991). "Antiserum from a patient with cerebellar degeneration identifies a novel protein in Purkinje cells, cortical neurons, and neuroectodermal tumors". J Neurosci. 11 (5): 1224–30. doi:10.1523/JNEUROSCI.11-05-01224.1991. PMC 6575333. PMID 1851215.
6. "Entrez Gene: AP3B2 adaptor-related protein complex 3, beta 2 subunit".

External links

• Human AP3B2 genome location and AP3B2 gene details page in the UCSC Genome Browser.

Further reading

• Dell'Angelica EC, Ohno H, Ooi CE, et al. (1997). "AP-3: an adaptor-like protein complex with ubiquitous expression". EMBO J. 16 (5): 917–28. doi:10.1093/emboj/16.5.917. PMC 1169692. PMID 9118953.
• Dell'Angelica EC, Klumperman J, Stoorvogel W, Bonifacino JS (1998). "Association of the AP-3 adaptor complex with clathrin". Science. 280 (5362): 431–4. Bibcode:1998Sci...280..431D. doi:10.1126/science.280.5362.431. PMID 9545220.
• Lim DS, Kirsch DG, Canman CE, et al. (1998). "ATM binds to beta-adaptin in cytoplasmic vesicles". Proc. Natl. Acad. Sci. U.S.A. 95 (17): 10146–51. Bibcode:1998PNAS...9510146L. doi:10.1073/pnas.95.17.10146. PMC 21476. PMID 9707615.
• Faundez VV, Kelly RB (2000). "The AP-3 complex required for endosomal synaptic vesicle biogenesis is associated with a casein kinase Ialpha-like isoform". Mol. Biol. Cell. 11 (8): 2591–604. doi:10.1091/mbc.11.8.2591. PMC 14942. PMID 10930456.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Dubois T, Zemlickova E, Howell S, Aitken A (2003). "Centaurin-alpha 1 associates in vitro and in vivo with nucleolin". Biochem. Biophys. Res. Commun. 301 (2): 502–8. doi:10.1016/S0006-291X(02)03010-3. PMID 12565890.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Chen C, Zou X, Ji C, et al. (2007). "Characterization of AP3B2_v2, a novel splice variant of human AP3B2". DNA Seq. 18 (3): 165–8. doi:10.1080/10425170600842121. PMID 17453999. S2CID 725773.

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