Acefurtiamine - Misplaced Pages

Chemical compound Pharmaceutical compound

Acefurtiamine
Clinical data

ATC code	none
Identifiers
IUPAC name (3E)-4-{(formyl)amino}-3-pent-3-en-1-yl (acetyloxy)acetate
CAS Number	10072-48-7
PubChem CID	3037171
ChemSpider	2300987
UNII	6APJ3D1308
ChEMBL	ChEMBL2104090
CompTox Dashboard (EPA)	DTXSID20864202
Chemical and physical data
Formula	C₂₁H₂₄N₄O₇S
Molar mass	476.50 g·mol
3D model (JSmol)	Interactive image
SMILES O=C(OCC(=O)OCCC(\SC(=O)c1occc1)=C(/N(C=O)Cc2cnc(nc2N)C)C)C
InChI InChI=1S/C21H24N4O7S/c1-13(25(12-26)10-16-9-23-14(2)24-20(16)22)18(33-21(29)17-5-4-7-30-17)6-8-31-19(28)11-32-15(3)27/h4-5,7,9,12H,6,8,10-11H2,1-3H3,(H2,22,23,24)/b18-13+ Key:MYBUGVXNAHWTOL-QGOAFFKASA-N
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Acefurtiamine (INN) is a vitamin B₁ analog in a manner similar to the GABAergic activity of the thiamine derivative clomethiazole. It functions as an analgesic agent at sufficient doses.

References

Martindale W (1993). The Extra Pharmacopoeia. Pharmaceutical Press. p. 1053. ISBN 978-0-85369-300-0.

A	α-Carotene β-Carotene Retinol Tretinoin
D	D₂ Ergosterol Ergocalciferol D₃ 7-Dehydrocholesterol Previtamin D₃ Cholecalciferol 25-hydroxycholecalciferol Calcitriol (1,25-dihydroxycholecalciferol) Calcitroic acid D₄ Dihydroergocalciferol D₅ D analogues Alfacalcidol Dihydrotachysterol Calcipotriol Tacalcitol Paricalcitol
E	Tocopherol Alpha Beta Gamma Delta Tocotrienol Alpha Beta Gamma Delta Tocofersolan
K	Naphthoquinone Phylloquinone (K₁) Menaquinones (K₂) Menadione (K₃) Various (K₄) 4-Amino-2-methyl-1-naphthol (K₅) 2-Methylnaphthalene-1,4-diamine (K₆) 4-Amino-3-methyl-1-naphthol (K₇)

Water
soluble

Combinations

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