| adenosylcobinamide hydrolase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.5.1.90 | ||||||||
| CAS no. | 905988-16-1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, an adenosylcobinamide hydrolase (EC 3.5.1.90) is an enzyme that catalyzes the chemical reaction
- adenosylcobinamide + H2O adenosylcobyric acid + (R)-1-aminopropan-2-ol
adenosylcobyric acid + (R)-1-aminopropan-2-olThus, the two substrates of this enzyme are adenosylcobinamide and H2O, whereas its two products are adenosylcobyric acid and (R)-1-aminopropan-2-ol.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is adenosylcobinamide amidohydrolase. Other names in common use include CbiZ, and AdoCbi amidohydrolase. This enzyme participates in porphyrin and chlorophyll metabolism.
References
- Woodson JD, Escalante-Semerena JC (2004). "CbiZ, an amidohydrolase enzyme required for salvaging the coenzyme B12 precursor cobinamide in archaea". Proc. Natl. Acad. Sci. U.S.A. 101 (10): 3591–6. Bibcode:2004PNAS..101.3591W. doi:10.1073/pnas.0305939101. PMC 373507. PMID 14990804.
| Hydrolases: carbon-nitrogen non-peptide (EC 3.5) | |
|---|---|
| 3.5.1: Linear amides / Amidohydrolases | |
| 3.5.2: Cyclic amides/ Amidohydrolases | |
| 3.5.3: Linear amidines/ Ureohydrolases | |
| 3.5.4: Cyclic amidines/ Aminohydrolases | |
| 3.5.5: Nitriles/ Aminohydrolases | |
| 3.5.99: Other | |
| Enzymes | |
|---|---|
| Activity | |
| Regulation | |
| Classification | |
| Kinetics | |
| Types |
|
This EC 3.5 enzyme-related article is a stub. You can help Misplaced Pages by expanding it. |