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Albumin_I
Solution structure of PA1b. PDB entry 1p8b
Identifiers
Symbol	Albumin_I
Pfam	PF08027
Pfam clan	CL0083
InterPro	IPR012512
Available protein structures: Pfam   structures / ECOD   PDB RCSB PDB; PDBe; PDBj PDBsum structure summary

Albumin I (PA1b) is a hormone-like peptide found in the seeds of legumes such as the pea plant (Pisum sativum) or soya bean (Glycine max) which have been shown to have insecticidal properties. It stimulates kinase activity upon binding a membrane bound 43 kDa receptor within the plant which affects cell proliferation. The structure reveals an inhibitor cystine knot (knottin)-like fold, comprising three beta strands.

References

1. ^ Jouvensal, L.; Quillien, L.; Ferrasson, E.; Rahbé, Y.; Guéguen, J.; Vovelle, F. O. (2003). "PA1b, an Insecticidal Protein Extracted from Pea Seeds (Pisum sativum): 1H-2-D NMR Study and Molecular Modeling†,‡". Biochemistry. 42 (41): 11915–11923. doi:10.1021/bi034803l. PMID 14556622.
2. ^ Da Silva, P.; Rahioui, I.; Laugier, C.; Jouvensal, L.; Meudal, H.; Chouabe, C.; Delmas, A. F.; Gressent, F. (2010). "Molecular Requirements for the Insecticidal Activity of the Plant Peptide Pea Albumin 1 Subunit b (PA1b)". Journal of Biological Chemistry. 285 (43): 32689–32694. doi:10.1074/jbc.M110.147199. PMC 2963353. PMID 20660598.
3. ^ Yamazaki T, Takaoka M, Katoh E, Hanada K, Sakita M, Sakata K, Nishiuchi Y, Hirano H (March 2003). "A possible physiological function and the tertiary structure of a 4-kDa peptide in legumes". Eur. J. Biochem. 270 (6): 1269–76. doi:10.1046/j.1432-1033.2003.03489.x. PMID 12631285.

• Plant peptide hormones