Alexamenus or Alexamenos may refer to:
- Alexamenus of Aetolia, Aetolian general in 196 BC
- Alexamenus of Teos (5th century BC?), a candidate for inventor of Greek literary genre of prose dialogue
See also
- Alexamenos graffito, an inscription in Rome from around 200 AD(?) often called the earliest depiction of Jesus
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