Misplaced Pages

Almokalant

Article snapshot taken from Wikipedia with creative commons attribution-sharealike license. Give it a read and then ask your questions in the chat. We can research this topic together.
Chemical compound Pharmaceutical compound
Almokalant
Clinical data
ATC code
  • None
Identifiers
IUPAC name
  • 4-(3-{Ethylamino}-2-hydroxypropoxy)benzonitrile
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC18H28N2O3S
Molar mass352.49 g·mol
3D model (JSmol)
SMILES
  • O=S(CCC)CCCN(CC)CC(O)COc1ccc(C#N)cc1
InChI
  • InChI=1S/C18H28N2O3S/c1-3-11-24(22)12-5-10-20(4-2)14-17(21)15-23-18-8-6-16(13-19)7-9-18/h6-9,17,21H,3-5,10-12,14-15H2,1-2H3
  • Key:ZMHOBBKJBYLXFR-UHFFFAOYSA-N
  (verify)

Almokalant is a drug used to treat arrhythmia. It is a potassium channel blocker. It has been found to have teratogenic effects in rats.

See also

References

  1. ^ Wiesfeld AC, Crijns HJ, Bergstrand RH, Almgren O, Hillege HL, Lie KI (October 1993). "Torsades de pointes with Almokalant, a new class III antiarrhythmic drug". American Heart Journal. 126 (4): 1008–1011. doi:10.1016/0002-8703(93)90726-p. PMID 8213422.
  2. Wellfelt K, Sköld AC, Wallin A, Danielsson BR (1999-04-01). "Teratogenicity of the class III antiarrhythmic drug almokalant. Role of hypoxia and reactive oxygen species". Reproductive Toxicology. 13 (2): 93–101. Bibcode:1999RepTx..13...93W. doi:10.1016/s0890-6238(98)00066-5. PMID 10213516.
Stub icon

This drug article relating to the cardiovascular system is a stub. You can help Misplaced Pages by expanding it.

Categories: