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Anhydrosialidase

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Anhydrosialidase
Identifiers
EC no.4.2.2.15
CAS no.157857-11-9
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The enzyme anhydrosialidase (EC 4.2.2.15) catalyzes the following process:

Elimination of α-sialyl groups in N-acetylneuraminic acid glycosides, releasing 2,7-anhydro-α-N-acetylneuraminate

This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on polysaccharides. The systematic name of this enzyme class is glycoconjugate sialyl-lyase (2,7-cyclizing). Other names in common use include anhydroneuraminidase, sialglycoconjugate N-acylneuraminylhydrolase (2,7-cyclizing), and sialidase L.

References

  • Li YT, Nakagawa H, Ross SA, Hansson GC, Li SC (1990). "A novel sialidase which releases 2,7-anhydro-α-N-acetylneuraminic acid from sialoglycoconjugates". J. Biol. Chem. 265 (35): 21629–33. PMID 2254319.
Carbon–oxygen lyases (EC 4.2) (primarily dehydratases)
4.2.1: Hydro-Lyases
4.2.2: Acting on polysaccharides
4.2.3: Acting on phosphates
4.2.99: Other
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