| Aspartate—ammonia ligase (ADP-forming) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 6.3.1.4 | ||||||||
| CAS no. | 37318-61-9 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, an aspartate—ammonia ligase (ADP-forming) (EC 6.3.1.4) is an enzyme that catalyzes the chemical reaction
- ATP + L-aspartate + NH3 ADP + phosphate + L-asparagine
ADP + phosphate + L-asparagineThe 3 substrates of this enzyme are ATP, L-aspartate, and NH3, whereas its 3 products are ADP, phosphate, and L-asparagine.
This enzyme belongs to the family of ligases, specifically those forming carbon-nitrogen bonds as acid-D-ammonia (or amine) ligases (amide synthases). The systematic name of this enzyme class is L-aspartate:ammonia ligase (ADP-forming). Other names in common use include asparagine synthetase (ADP-forming), and asparagine synthetase (adenosine diphosphate-forming). This enzyme participates in nitrogen metabolism.
References
- Nair PM (September 1969). "Asparagine synthetase from gamma-irradiated potatoes". Archives of Biochemistry and Biophysics. 133 (2): 208–15. doi:10.1016/0003-9861(69)90447-0. PMID 5820987.
| Enzymes: CO CS and CN ligases (EC 6.1-6.3) | |
|---|---|
| 6.1: Carbon-Oxygen | |
| 6.2: Carbon-Sulfur | |
| 6.3: Carbon-Nitrogen | |
| Enzymes | |
|---|---|
| Activity | |
| Regulation | |
| Classification | |
| Kinetics | |
| Types |
|
This EC 6.3 enzyme-related article is a stub. You can help Misplaced Pages by expanding it. |