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Avermitilol synthase

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Avermitilol synthase
Identifiers
EC no.4.2.3.96
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IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
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MetaCycmetabolic pathway
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Avermitilol synthase (EC 4.2.3.96) is an enzyme with systematic name avermitilol hydrolase (cyclizing, avermitilol-forming). This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate + H2O {\displaystyle \rightleftharpoons } avermitilol + diphosphate

This enzyme requires Mg.

References

  1. Chou WK, Fanizza I, Uchiyama T, Komatsu M, Ikeda H, Cane DE (July 2010). "Genome mining in Streptomyces avermitilis: cloning and characterization of SAV_76, the synthase for a new sesquiterpene, avermitilol". Journal of the American Chemical Society. 132 (26): 8850–1. doi:10.1021/ja103087w. PMC 2904616. PMID 20536237.

External links

Carbon–oxygen lyases (EC 4.2) (primarily dehydratases)
4.2.1: Hydro-Lyases
4.2.2: Acting on polysaccharides
4.2.3: Acting on phosphates
4.2.99: Other
Enzymes
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