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Other names beta-MSH, β-melanotropin, β-melanocortin, β-intermedin | |
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Chemical formula | C118H174N34O35S |
Molar mass | 2660.95 g·mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Infobox references |
β-Melanocyte-stimulating hormone (β-MSH) is an endogenous peptide hormone and neuropeptide. It is a melanocortin, specifically, one of the three types of melanocyte-stimulating hormone (MSH), and is produced from proopiomelanocortin (POMC). It is an agonist of the MC1, MC3, MC4, and MC5 receptors.
β-MSH is also known to decrease food intake in animals such as rats, chicken due to the effect of proopiomelanocortin (POMC). Research was performed to see the effect β-MSH has on chicks, and it has been found that chicks responded with a decrease in food and water intake when treated with β-MSH. The experiment showed that β-MSH causes anorexigenic effects in chicks.
See also
References
- ^ Abba Kastin (26 January 2013). Handbook of Biologically Active Peptides. Academic Press. pp. 838–844. ISBN 978-0-12-385096-6.
- Kamisoyama, Hiroshi; Honda, Kazuhisa; Saneyasu, Takaoki; Sugahara, Kunio; Hasegawa, Shin (2009-07-24). "Corticotropin-releasing factor is a downstream mediator of the beta-melanocyte-stimulating hormone-induced anorexigenic pathway in chicks". Neuroscience Letters. 458 (3): 102–105. doi:10.1016/j.neulet.2009.04.041. ISSN 0304-3940. PMID 19393716. S2CID 42981014.
- Smith, M. L.; Prall, B.; Nandar, W.; Cline, M. A. (February 2008). "Beta-melanocyte-stimulating hormone potently reduces appetite via the hypothalamus in chicks". Journal of Neuroendocrinology. 20 (2): 220–226. doi:10.1111/j.1365-2826.2007.01639.x. ISSN 1365-2826. PMID 18088360. S2CID 19661927.
Peptides: neuropeptides | |||||||||||
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Hormones | see hormones | ||||||||||
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Melanocortin receptor modulators | |
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MC1 |
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MC2 | |
MC3 | |
MC4 |
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MC5 |
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Unsorted | |
Others |
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