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CO 2 content (also known as "Total CO 2") is a blood test that usually appears on a "Chem 19" or an electrolyte panel. The value measures the total dissolved Carbon dioxide (CO 2) in blood. It is determined by combining the Bicarbonate (HCO 3) and the partial pressure of CO 2 multiplied by a factor which estimates the amount of pure CO 2 that is dissolved in its natural form (usually 0.03).