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Cardinal Piccolomini may refer to:
Enea Silvio Piccolomini, cardinal-priest of Santa Sabina from 1456, became Pope Pius II (r. 1458–1464)
Francesco Piccolomini, cardinal-deacon of San Eustachio from 1460, became Pope Pius III (r. 1503)
Celio Piccolomini (1609–1681), cardinal-priest of San Pietro in Montorio from 1664
Topics referred to by the same term
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This disambiguation page lists articles associated with the title Cardinal Piccolomini.