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Casbene synthase

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Enzyme
casbene synthase
Identifiers
EC no.4.2.3.8
CAS no.69106-45-2
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BRENDABRENDA entry
ExPASyNiceZyme view
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MetaCycmetabolic pathway
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The enzyme casbene synthase (EC 4.2.3.8) catalyzes the chemical reaction

geranylgeranyl diphosphate {\displaystyle \rightleftharpoons } casbene + diphosphate

This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on phosphates. The systematic name of this enzyme class is geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, casbene-forming). Other names in common use include casbene synthetase, and geranylgeranyl-diphosphate diphosphate-lyase (cyclizing). This enzyme participates in diterpenoid biosynthesis.

References

  • Moesta P, West CA (1985). "Casbene synthetase: regulation of phytoalexin biosynthesis in Ricinus communis L. seedlings. Purification of casbene synthetase and regulation of its biosynthesis during elicitation". Arch. Biochem. Biophys. 238 (1): 325–33. doi:10.1016/0003-9861(85)90171-7. PMID 3985625.
Carbon–oxygen lyases (EC 4.2) (primarily dehydratases)
4.2.1: Hydro-Lyases
4.2.2: Acting on polysaccharides
4.2.3: Acting on phosphates
4.2.99: Other
Enzymes
Activity
Regulation
Classification
Kinetics
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