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Che1 RNA motif

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Conserved RNA structure
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RNA family
che1
Consensus secondary structure and sequence conservation of che1 RNA
Identifiers
Symbolche1
RfamRF02935
Other data
RNA typeGene; sRNA
SOSO:0001263
PDB structuresPDBe

The che1 RNA motif is a conserved RNA structure that was discovered by bioinformatics. che1 motifs are found in the genus Streptomyces, as well as some other organisms that are closely related to this genus.

It is ambiguous whether che1 RNAs function as cis-regulatory elements or whether they operate in trans. However, che1 RNAs are consistently located upstream of protein-coding genes, which are often predicted to function as cholesterol esterases. It is possible that che1 RNAs regulate these genes.

References

  1. Weinberg Z, Lünse CE, Corbino KA, Ames TD, Nelson JW, Roth A, Perkins KR, Sherlock ME, Breaker RR (October 2017). "Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions". Nucleic Acids Res. 45 (18): 10811–10823. doi:10.1093/nar/gkx699. PMC 5737381. PMID 28977401.
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