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CHRAC1
Identifiers
Aliases	CHRAC1, CHARC1, CHARC15, CHRAC-1, CHRAC-15, CHRAC15, YCL1, chromatin accessibility complex 1, chromatin accessibility complex subunit 1
External IDs	OMIM: 607268; MGI: 2135796; HomoloGene: 41174; GeneCards: CHRAC1; OMA:CHRAC1 - orthologs
Gene location (Human) Chr. Chromosome 8 (human) Band 8q24.3 Start 140,511,311 bp End 140,517,154 bp
Gene location (Mouse) Chr. Chromosome 15 (mouse) Band 15|15 D3 Start 72,962,241 bp End 72,969,403 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in pancreatic epithelial cell monocyte tibial arteries muscle of leg gastrocnemius muscle muscle of thigh tibialis anterior muscle smooth muscle tissue mucosa of ileum right coronary artery Top expressed in saccule otic placode seminiferous tubule spermatocyte otic vesicle spermatid fossa condyle muscle of thigh intercostal muscle More reference expression data BioGPS n/a
Gene ontology Molecular function transferase activity DNA binding DNA-directed DNA polymerase activity nucleotidyltransferase activity protein binding protein heterodimerization activity Cellular component epsilon DNA polymerase complex nucleus CHRAC Biological process DNA biosynthetic process chromatin remodeling Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 54108 93696 Ensembl ENSG00000104472 ENSMUSG00000068391 UniProt Q9NRG0 Q9JKP8 RefSeq (mRNA) NM_017444 NM_053068 RefSeq (protein) NP_059140 NP_444298 Location (UCSC) Chr 8: 140.51 – 140.52 Mb Chr 15: 72.96 – 72.97 Mb PubMed search
Wikidata
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Chromatin accessibility complex 1 is a protein that in humans is encoded by the CHRAC1 gene.

Function

CHRAC1 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.

References

1. ^ GRCh38: Ensembl release 89: ENSG00000104472 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000068391 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Chromatin accessibility complex 1". Retrieved 2016-10-26.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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