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cis-Muuroladiene synthase (EC 4.2.3.67, MxpSS1) is an enzyme with systematic name(2E,6E)-farnesyl-diphosphate diphosphate-lyase (cis-muuroladiene-forming). This enzyme catalyses the following chemical reactions
The recombinant enzyme from black peppermint produces a mixture of cis-muurola-3,5-diene and cis-muurola-4(14),5-diene.
References
Prosser IM, Adams RJ, Beale MH, Hawkins ND, Phillips AL, Pickett JA, Field LM (August 2006). "Cloning and functional characterisation of a cis-muuroladiene synthase from black peppermint (Mentha x piperita) and direct evidence for a chemotype unable to synthesise farnesene". Phytochemistry. 67 (15): 1564–71. doi:10.1016/j.phytochem.2005.06.012. PMID16083926.