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Clofexamide

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Chemical compound Pharmaceutical compound
Clofexamide
Clinical data
Routes of
administration		Oral, rectal, topical
ATC code
  • None
Legal status
Legal status
  • Discontinued
Identifiers
IUPAC name
  • 2-(4-Chlorophenoxy)-N-acetamide
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.013.592 Edit this at Wikidata
Chemical and physical data
FormulaC14H21ClN2O2
Molar mass284.78 g·mol
3D model (JSmol)
SMILES
  • CCN(CC)CCNC(=O)COC1=CC=C(C=C1)Cl
InChI
  • InChI=1S/C14H21ClN2O2/c1-3-17(4-2)10-9-16-14(18)11-19-13-7-5-12(15)6-8-13/h5-8H,3-4,9-11H2,1-2H3,(H,16,18)
  • Key:UORGKWWJEQDTGX-UHFFFAOYSA-N

Clofexamide (or amichlophene) is an antidepressant that was a component of the drug combination clofezone, the other being the nonsteroidal anti-inflammatory drug (NSAID) phenylbutazone. Clofezone was used to treat joint and muscular pain, but is not marketed any more.

References

  1. Berger A, Wachter H, eds. (1998). Hunnius Pharmazeutisches Wörterbuch (in German) (8 ed.). Walter de Gruyter Verlag. p. 343. ISBN 3-11-015793-4.
  2. Reinicke C, Helbing M, Klingenfeld U, Lasaroff I, Wessel G (December 1984). "". Die Pharmazie. 39 (12): 824–7. PMID 6241720.
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