Cortelyou is a surname. Notable people with the surname include:
- Jacques Cortelyou (c. 1625–1693), Surveyor General of New Netherland
- George B. Cortelyou (1862–1940), first US Secretary of Commerce and Labor and later Secretary of the Treasury
- Philip Cortelyou Johnson (1906–2005), American architect
See also
- Cortelyou, Alabama
- Cortelyou Road (BMT Brighton Line), a rapid-transit station in Brooklyn, New York
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