Cruse may refer to:
- Cruse (surname), a list of people and a fictional character with this name
- Cruse Bereavement Care, a UK charity
- Cruse, Illinois, United States, an unincorporated community
- Cruse Memorial Heliport, a private heliport in Douglas County, Oregon, United States
See also
- Cruise (disambiguation)
- Cruz (disambiguation)
- Cruze (disambiguation)
- Widow's cruse: a reference to a story involving Elijah
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