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Cycrimine

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Chemical compound Pharmaceutical compound
Cycrimine
Clinical data
License data
ATC code
  • none
Identifiers
IUPAC name
  • 1-Cyclopentyl-1-phenyl-3-(piperidin-1-yl)propan-1-ol
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.000.932 Edit this at Wikidata
Chemical and physical data
FormulaC19H29NO
Molar mass287.447 g·mol
3D model (JSmol)
SMILES
  • OC(CCN1CCCCC1)(C2CCCC2)c3ccccc3
InChI
  • InChI=1S/C19H29NO/c21-19(18-11-5-6-12-18,17-9-3-1-4-10-17)13-16-20-14-7-2-8-15-20/h1,3-4,9-10,18,21H,2,5-8,11-16H2
  • Key:SWRUZBWLEWHWRI-UHFFFAOYSA-N

Cycrimine (trade name Pagitane) is a central anticholinergic drug designed to reduce the levels of acetylcholine in the treatment of Parkinson's disease. Its mechanism of action is to bind to the muscarinic acetylcholine receptor M1.

Synthesis

Cycrimine synthesis:

See also

References

  1. Usdin E, Efron DH, eds. (1979). Psychotropic Drugs and Related Compounds (2nd ed.). Washington, DC: Pergamon Press. p. 218. ISBN 978-0-08-025510-1. OCLC 715151908.
  2. Denton JJ, Schedl HP, Lawson VA, Neier WB (1950). "Antispasmodics. VII. Additional Morpholinyl and Piperidyl Tertiary Alcohols". Journal of the American Chemical Society. 72 (8): 3795–3796. doi:10.1021/ja01164a127.

External links

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