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DNER
Identifiers
Aliases	DNER, UNQ26, bet, delta/notch like EGF repeat containing
External IDs	OMIM: 607299; MGI: 2152889; HomoloGene: 26722; GeneCards: DNER; OMA:DNER - orthologs
Gene location (Human) Chr. Chromosome 2 (human) Band 2q36.3 Start 229,357,629 bp End 229,714,555 bp
Gene location (Mouse) Chr. Chromosome 1 (mouse) Band 1|1 C5 Start 84,347,560 bp End 84,673,942 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in lateral nuclear group of thalamus cerebellar vermis pars reticulata pars compacta parotid gland subthalamic nucleus external globus pallidus inferior ganglion of vagus nerve superior vestibular nucleus internal globus pallidus Top expressed in lobe of cerebellum cerebellar vermis ventromedial nucleus barrel cortex piriform cortex habenula mammillary body ventral tegmental area deep cerebellar nuclei substantia nigra More reference expression data BioGPS More reference expression data
Gene ontology Molecular function clathrin binding calcium ion binding protein binding transmembrane signaling receptor activity Notch binding Cellular component integral component of membrane soma plasma membrane dendrite early endosome membrane Biological process Notch receptor processing synapse assembly central nervous system development neuron migration endocytosis glial cell differentiation skeletal muscle fiber development Notch signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 92737 227325 Ensembl ENSG00000187957 ENSMUSG00000036766 UniProt Q8NFT8 Q8JZM4 RefSeq (mRNA) NM_139072 NM_152915 RefSeq (protein) NP_620711 NP_690879 Location (UCSC) Chr 2: 229.36 – 229.71 Mb Chr 1: 84.35 – 84.67 Mb PubMed search
Wikidata
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Delta and Notch-like epidermal growth factor-related receptor is a protein that in humans is encoded by the DNER gene.

References

1. ^ GRCh38: Ensembl release 89: ENSG00000187957 – Ensembl, May 2017
2. ^ GRCm38: Ensembl release 89: ENSMUSG00000036766 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Eiraku M, Hirata Y, Takeshima H, Hirano T, Kengaku M (Jul 2002). "Delta/notch-like epidermal growth factor (EGF)-related receptor, a novel EGF-like repeat-containing protein targeted to dendrites of developing and adult central nervous system neurons". J Biol Chem. 277 (28): 25400–7. doi:10.1074/jbc.M110793200. PMID 11950833.
6. Nishizumi H, Komiyama T, Miyabayashi T, Sakano S, Sakano H (May 2002). "BET, a novel neuronal transmembrane protein with multiple EGF-like motifs". NeuroReport. 13 (6): 909–15. doi:10.1097/00001756-200205070-00035. PMID 11997712. S2CID 8325151.
7. "Entrez Gene: DNER delta/notch-like EGF repeat containing".

Further reading

• Sanger Centre, The; Washington University Genome Sequencing Cente, The (1999). "Toward a complete human genome sequence". Genome Res. 8 (11): 1097–108. doi:10.1101/gr.8.11.1097. PMID 9847074.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4". Nature. 434 (7034): 724–31. Bibcode:2005Natur.434..724H. doi:10.1038/nature03466. PMID 15815621.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
• Ramachandran P, Boontheung P, Xie Y, et al. (2006). "Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry". J. Proteome Res. 5 (6): 1493–503. doi:10.1021/pr050492k. PMID 16740002.

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