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Diffractaic acid

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Chemical compound produced by lichens
Diffractaic acid
Names
IUPAC name 4-(2,4-dimethoxy-3,6-dimethylbenzoyl)oxy-2-hydroxy-3,6-dimethylbenzoic acid
Other names Diffractic acid, Dirbizomic acid, Dirhizomic acid, NSC 5901,NSC 685595
Identifiers
CAS Number
3D model (JSmol)
ChEMBL
ChemSpider
PubChem CID
CompTox Dashboard (EPA)
InChI
  • InChI=1S/C20H22O7/c1-9-8-14(11(3)17(21)15(9)19(22)23)27-20(24)16-10(2)7-13(25-5)12(4)18(16)26-6/h7-8,21H,1-6H3,(H,22,23)Key: MIJKZXWOOXIEEU-UHFFFAOYSA-N
SMILES
  • O=C(O)C1=C(O)C(C)=C(OC(C2=C(OC)C(C)=C(OC)C=C2C)=O)C=C1C
Properties
Chemical formula C20H22O7
Molar mass 374.389 g·mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Infobox references
Chemical compound

Diffractaic acid is a β-orcinol depside with the molecular formula C20H22O7, which is produced by lichens. Diffractaic acid has cytotoxic, cytogenetic, oxidative, analgesic and antiviral effects.

The foliose lichen species Punctelia diffractaica is named for the presence of this compound.

References

  1. ^ "Diffractaic acid". Pubchem.ncbi.NLM.nih.gov.
  2. ^ "Diffractaic Acid (CAS 436-32-8)". www.caymanchem.com.
  3. Sukumaran, Swapna Thacheril; Sugathan, Shiburaj; Abdulhameed, Sabu (28 November 2020). Plant Metabolites: Methods, Applications and Prospects. Springer Nature. p. 265. ISBN 978-981-15-5136-9.
  4. ^ Demir, Leyla; Toğar, Başak; Türkez, Hasan; Sozio, Piera; Aslan, Ali; Stefano, Antonio Di (2015). "The investigation of cytogenetic and oxidative effects of diffractaic acid on human lymphocyte cultures". Brazilian Archives of Biology and Technology. 58: 75–81. doi:10.1590/S1516-8913201502752. ISSN 1516-8913.
  5. Kurokawa, S. (1999). "Notes on Flavopunctelia and Punctelia (Parmeliaceae), with descriptions of four new species". Bulletin of the Botanical Garden of Toyama. 4: 25–32.

Further reading

  • Sinha, Rajeshwar P.; Häder, h c Donat-P. (6 October 2020). Natural Bioactive Compounds: Technological Advancements. Academic Press. p. 257. ISBN 978-0-12-820659-1.


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