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DnaE

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DNA pol III alpha subunit aka DNA Enus
Identifiers
OrganismEscherichia coli
(str. K-12 substr. MG1655)
SymboldnaE
Entrez944877
PDB2HNH
RefSeq (Prot)NP_414726.1
UniProtP10443
Other data
EC number2.7.7.7
Chromosomegenome: 0.2 - 0.21 Mb
Search for
StructuresSwiss-model
DomainsInterPro
Protein family
Bacterial DNA polymerase III alpha subunit
Identifiers
SymbolDNA_pol3_alpha
PfamPF07733
InterProIPR011708
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary

DnaE, the gene product of dnaE, is the catalytic α subunit of DNA polymerase III, acting as a DNA polymerase. This enzyme is only found in prokaryotes.

References

  1. Wu H, Hu Z, Liu XQ (August 1998). "Protein trans-splicing by a split intein encoded in a split DnaE gene of Synechocystis sp. PCC6803". Proceedings of the National Academy of Sciences of the United States of America. 95 (16): 9226–31. doi:10.1073/pnas.95.16.9226. PMC 21320. PMID 9689062.
DNA replication (comparing prokaryotic to eukaryotic)
Initiation
Prokaryotic
(initiation)
Eukaryotic
(preparation in
G1 phase)
Both
Replication
Prokaryotic
(elongation)
Eukaryotic
(synthesis in
S phase)
Both
Termination
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