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Dolichylation

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In biochemistry, dolichylation is the covalent addition of a dolichol group to a protein. This post-translational modification has been shown to occur in a number of eukaryotes, including the malarial parasite Plasmodium falciparum.

References

  1. Hjertman, M.; Wejde, J.; Dricu, A.; Carlberg, M.; Griffiths, W. J.; Sjövall, J.; Larsson, O. (1997). "Evidence for protein dolichylation". FEBS Letters. 416 (3): 235–238. doi:10.1016/S0014-5793(97)01208-8. PMID 9373159.
  2. Dalexandri, F.; Kimura, E.; Peres, V.; Katzin, A. (2006). "Protein dolichylation in Plasmodium falciparum". FEBS Letters. 580 (27): 6343–6348. doi:10.1016/j.febslet.2006.10.042. PMID 17084391.
Protein primary structure and posttranslational modifications
General
N terminus
C terminus
Single specific AAs
Serine/Threonine
Tyrosine
Cysteine
Aspartate
Glutamate
Asparagine
Glutamine
Lysine
Arginine
Proline
Histidine
Tryptophan
Crosslinks between two AAs
CysteineCysteine
MethionineHydroxylysine
LysineTyrosine
TryptophanTryptophan
Crosslinks between three AAs
SerineTyrosineGlycine
HistidineTyrosineGlycine
AlanineSerineGlycine
Crosslinks between four AAs
AllysineAllysineAllysineLysine
Category: