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Cranioschisis (Greek: κρανιον kranion, "skull", and σχίσις schisis, "split") is a skull-related neural tube defect. The skull does not close all the way in this deformity (especially at the occipital region). As a result, the amniotic fluid enters the brain, leading to eventual brain degeneration and anencephaly. Craniorachischisis is on the extreme end of the dysraphism spectrum, wherein the entire length of the neural tube fails to close.

See also

• Rachischisis
• Spina bifida

References

1. Singh, D.R. (2017). Essentials of Anatomy for Dentistry Students. Wolters Kluwer India Pvt. Limited. p. 359. ISBN 978-93-5129-620-1. Retrieved January 2, 2024.
2. Larsen's Human Embryology (5 ed.). Churchill Livingstone. 2015. pp. 81–107.

Further reading

• Marin-Padilla, Miguel (1965). "Study of the Skull in Human Cranioschisis". Cells Tissues Organs. 62 (1). S. Karger AG: 1–20. doi:10.1159/000142740. ISSN 1422-6405. PMID 5864445.
• Padmanabhan, R. (1988). "Light microscopic studies on the pathogenesis of exencephaly and cranioschisis induced in the rat after neural tube closure". Teratology. 37 (1): 29–36. doi:10.1002/tera.1420370106. ISSN 0040-3709. PMID 3347905.

External links

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