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Epomediol

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Synthetic terpenoid Pharmaceutical compound
Epomediol
Skeletal formula
Ball-and-stick model
Clinical data
Other names1,3,3-Trimethyl-2-oxabicyclo octane-6,7-endo,endo-diol
ATC code
Identifiers
IUPAC name
  • (1s,4r,6R,7S)-1,3,3-trimethyl-2-oxabicyclooctane-6,7-diol
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC10H18O3
Molar mass186.251 g·mol
3D model (JSmol)
SMILES
  • OC1CC2C(OC1(C)C(O)C2)(C)C

Epomediol (trade name Clesidren) is a synthetic terpenoid with choleretic effects. It has been used in the symptomatic treatment of itching due to intrahepatic cholestasis of pregnancy.

References

  1. Gonzalez MC, Iglesias J, Tiribelli C, et al. (September 1992). "Epomediol ameliorates pruritus in patients with intrahepatic cholestasis of pregnancy". J Hepatol. 16 (1–2): 241–2. doi:10.1016/S0168-8278(05)80122-9. PMID 1484159.
  2. Reyes H (December 1992). "The spectrum of liver and gastrointestinal disease seen in cholestasis of pregnancy". Gastroenterol Clin North Am. 21 (4): 905–21. PMID 1478743.
  3. Reyes H, Simon FR (August 1993). "Intrahepatic cholestasis of pregnancy: an estrogen-related disease". Semin Liver Dis. 13 (3): 289–301. doi:10.1055/s-2007-1007357. PMID 8235718.
Bile and liver therapy (A05)
Bile therapy
Liver therapy


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