Er blood group system - Misplaced Pages

(Redirected from Er blood group collection) Human blood group classification

The Er blood group system consists of five human red blood cell surface antigens, Er, Er, Er3, Er4 and Er5. The incidences of Er and Er3 are each greater than 99% of the human population, while the incidence of Er is less than 0.01%. Er4 and Er5 are found at a high frequency in the general population.

Individuals with antibodies against Er3 may develop acute hemolytic transfusion reaction upon transfusion with an incompatible unit, while Er and Er are unlikely to be clinically significant. The clinical significance of antibodies against Er4 and Er5 is poorly understood due to a lack of data, but two cases of severe hemolytic disease of the fetus and newborn have been reported in women with these antibodies. Expression of the Er blood group antigens is controlled by the gene PIEZO1.

Er was first identified in 1982 and Er was identified in 1988. Er was recognized as a blood group collection by the International Society of Blood Transfusion in 1990 and promoted to a blood group in 2022.

References

^ Karamatic Crew, V.; Tilley, L.A.; Satchwell, T.J.; AlSubhi, S.A.; Jones, B.; Spring, F.A.; et al. (2022). "Missense mutations in PIEZO1, encoding the Piezo1 mechanosensor protein, define the Er red blood cell antigens". Blood. 141 (2): 135–146. doi:10.1182/blood.2022016504. PMC 10644042. PMID 36122374.
^ The Blood Group Antigen FactsBook, Elsevier, 2012, doi:10.1016/B978-0-12-415849-8.00038-7, ISBN 978-0-12-415849-8, retrieved 2021-01-28
Daniels, G. L.; Fletcher, A.; Garratty, G.; Henry, S.; Jørgensen, J.; Judd, W. J.; Levene, C.; Lomas-Francis, C.; Moulds, J. J.; Moulds, J. M.; Moulds, M. (November 2004). "Blood group terminology 2004: from the International Society of Blood Transfusion committee on terminology for red cell surface antigens". Vox Sanguinis. 87 (4): 304–316. doi:10.1111/j.1423-0410.2004.00564.x. hdl:2027.42/73460. ISSN 0042-9007. PMID 15585029. S2CID 1430414.
Modern blood banking & transfusion practices. Harmening, Denise. (6th ed.). Philadelphia: F.A. Davis. 2012. ISBN 978-0-8036-2682-9. OCLC 762374313.{{cite book}}: CS1 maint: others (link)

v t e Blood transfusion and transfusion medicine
Blood products	Whole blood Platelets Platelet transfusion Red blood cells Plasma Fresh frozen plasma PF24 Cryoprecipitate Cryosupernatant White blood cells Granulocyte transfusion Blood substitutes
General concepts	Blood bank Blood donation Blood management International Society of Blood Transfusion ISBT 128
Methods	Apheresis (plasmapheresis, plateletpheresis, leukapheresis) Exchange transfusion Intraoperative blood salvage
Tests	Blood compatibility testing Cross-matching Coombs test Kleihauer–Betke test Antibody elution Monocyte monolayer assay
Transfusion reactions and adverse effects	Transfusion hemosiderosis Transfusion related acute lung injury Transfusion associated circulatory overload Transfusion-associated graft versus host disease Febrile non-hemolytic transfusion reaction Hemolytic reaction acute delayed Serum sickness Transfusion transmitted infection
Blood group systems	Blood types ABO Secretor status Augustine CD59 Chido-Rodgers Colton Cromer Diego Dombrock Duffy Er FORS Gerbich GIL GLOB Hh Ii Indian JR JMH KANNO Kell (Xk) Kidd Knops Lan Lewis Lutheran LW MNS OK P1PK Raph Rh and RHAG Scianna Sid T-Tn Vel Xg Yt Other

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