Esmaeil is a given name. Notable people with the name include:
- Esmaeil Bale (born 1985), Iranian footballer
- Esmaeil Dousti, Iranian reformist politician, member of the City Council of Tehran
- Esmaeil Ebadi (born 1976), Iranian archer who won the gold medal at the 2014 Asian Games
- Esmaeil Elmkhah (8206–1988), Iranian featherweight weightlifter
- Esmaeil Farhadi (born 1982), Iranian football player
- Esmaeil Halali (born 1973), Iranian retired football player and manager of Mes Soongoun
- Esmaeil Hosseini (born 1942), former Iranian cyclist
- Esmaeil Jabbarzadeh (born 1960), Iranian reformist politician, former Governor of East Azerbaijan, Iran from 2013 to 2017
- Esmaeil Khatib (born 1961), Iranian cleric and politician
- Esmaeil Kousari (born 1955), Iranian military officer and conservative politician, currently the deputy chief of Sarallah Headquarters
- Esmaeil Pashapour (born 1954), Iranian fencer
- Esmaeil Sedigh, Iranian futsal coach and instructor based in the Philippines
- Esmaeil Sharifat (born 1988), Iranian football player
- Esmaeil Sohrabi, Iranian retired military officer and Chief-of-Staff of the Islamic Republic of Iran Army from 1984 to 1988
- Seyed Esmaeil Mousavi Zanjani (1928–2002), Iranian Shiite cleric and politician
- Mid name
- Mohammad Vahid Esmaeil Beigi (born 1992), Iranian football defender
- Mohammad Esmaeil Saeidi (born 1961), Iranian retired Revolutionary Guards commander and politician affiliated with the Front of Islamic Revolution Stability
- Mohammad Esmaeil Shooshtari (born 1949), minister of justice of the Islamic Republic of Iran for 1997–2005
See also
- Hajj Esmaeil, a village in Bizaki Rural District, Golbajar District, Chenaran County, Razavi Khorasan Province, Iran
- Emamzadeh Esmaeil and Isaiah mausoleum, historical complex in Isfahan, Iran, which dates back to the Seljuk and Safavid era
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